ADH

Optimal Result: 0 - 4.7 pg/mL.

From Healthmatters.io Team

Lab Results Explained and Tracked

ADH stands for antidiuretic hormone also known as vasopressin. ADH primarily acts in the kidney to resorb water. Vasopressin can also be administered to raise blood pressure. ADH is produced by the hypothalamus and released into the bloodstream by the pituitary gland. ADH levels increase in response to low blood volume. Thus in times of dehydration or hemorrhage, ADH works to increase the amount of water in the bloodstream by decreasing water loss and kidney. This increased water retention will also dilute the amount of sodium in the blood, causing sodium levels to decrease. On the other hand, the pituitary stops releasing ADH in response to decreased sodium levels in the blood, acting as a feedback mechanism.

Normal Ranges for ADH:

1 to 5 pg/mL

Sources:

https://medlineplus.gov/ency/article/003702.htm

https://www.uptodate.com/contents/general-principles-of-disorders-of-water-balance-hyponatremia-and-hypernatremia-and-sodium-balance-hypovolemia-and-edema

https://www.uptodate.com/contents/pathophysiology-and-etiology-of-the-syndrome-of-inappropriate-antidiuretic-hormone-secretion-siadh

https://emedicine.medscape.com/article/246650-clinical

https://www.uptodate.com/contents/diagnosis-of-polyuria-and-diabetes-insipidus

Lab Results Explained and Tracked

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What does it mean if your ADH result is too high?

The causes of high ADH levels are collectively known as syndrome of inappropriate antidiuretic hormone secretion or SIADH. In SIADH, the body cannot excrete sufficient amounts of water because ADH levels are chronically too high. As a result, sodium levels drop resulting in hyponatremia. If sodium levels drop slowly, there may be no or only subtle symptoms. If sodium levels drop rapidly, severe symptoms may occur, even death. Gradual hyponatremia causes slowed reaction times, cognitive slowness, and problems with balance and walking. Early symptoms of quickly dropping sodium include a lack of appetite, nausea, and malaise. This is followed by headache, muscle cramps, irritability, drowsiness, confusion, weakness, seizures, and coma. There are several causes of SIADH ranging from mental and neurological disorders, cancer, lung disease, genetic disorders and many medications.

Some specific causes of high ADH are:

- Stroke

- Psychosis

- Head trauma

- Brain tumor

- Surgery

- Lung tumor

- Porphyria

- Hereditary SIADH

- Old age

- Medications

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What does it mean if your ADH result is too low?

Low levels of ADH may not be detectable on laboratory tests. In fact, some labs do not list a lower level of normal on their results. That said, people without the ability to produce ADH have a condition called central diabetes insipidus. In this condition, people cannot resorb water in the kidneys so they drink and urinate almost constantly. It is treated by administering ADH.

Some specific causes of low ADH are:

- Central diabetes insipidus

- Brain tumor

- Brain hemorrhage

- Primary polydipsia

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ADH

All Your Lab Results. One Simple Dashboard.

What does it mean if your ADH result is too high?

All Your Lab Results. One Simple Dashboard.

Import, Track, and Share Your Lab Results Easily

Import, Track, and Share Your Lab Results

What does it mean if your ADH result is too low?

Article Review & Sources

Bring All Your Lab Results Together — In One Place

Gather Your Lab History — and Finally Make Sense of It

Finally, Your Lab Results Organized and Clear

Advanced Plan

Unlimited Account

Pro Monthly

What's included in a Healthmatters membership

Import Lab Results from Any Source

See Your Health Timeline

Understand What Your Results Mean

Enter Your Lab Reports Yourself — Always Free Enter Your Lab Reports — Always Free

Visualize Your Results

Export Your Complete Lab History in a Single File Export Your Complete Lab History

Comprehensive Data Entry Service for Your Reports Data Entry Service for Your Reports

Securely Share With Anyone You Trust

Let Your Lab Results Tell the Full Story

Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.

Bring all your results together to compare, track progress, export your history, and share securely.

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All Your Lab Results.
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