Diethyldithiophosphate (DEDTP) is a metabolite of organophosphates, which are one of the most common causes of poisoning worldwide and are frequently intentionally used as pesticides. They can enter the body through the lungs or skin, or by eating contaminated food. Even at low levels, organophosphates may be hazardous to the nervous system, especially for foetuses and young children. Repeated or prolonged exposure may induce impaired memory and concentration, disorientation, severe depression, irritability, confusion, headache, speech diculties, delayed reaction times, nightmares, sleepwalking, drowsiness, or insomnia. Organophosphates function by inhibiting the action of cholinesterase enzymes in nerve cells. An inuenza-like condition with headache, nausea, weakness, loss of appetite, and malaise.
Keeping track of your medical data and laboratory results while understanding what they mean empowers positive health outcomes.
Keeping track of your medical data and lab results while understanding what they mean empowers positive health outcomes.
Save 10% off any plan with promo-code:
HEALTH10
Elevated levels of Diethyldithiophosphate (DEDTP) are significant as DEDTP is a metabolite formed by the biotransformation of organophosphorous (OP) pesticides. It has a longer half-life than its parent compound, suggesting a persistent presence in the body once exposure has occurred.
Research has shown that DEDTP can induce genotoxic and immunotoxic effects:
Genotoxicity refers to the compound's ability to damage genetic information in cells, which can lead to mutations and potentially contribute to the development of cancer.
Immunotoxicity refers to the ability of a substance to affect the immune system. DEDTP has been associated with increased tumor size and a reduced response of lymphocytes to tumor antigens, suggesting that it could affect the growth of tumors and alter immune responses at environmentally relevant concentrations.
Furthermore, DEDTP has been found to show immunotoxic effects on T cells and natural killer cells, as well as immunomodulatory effects on macrophages, which are critical components of the immune system. These effects could modify the body's response to tumors and other immunological challenges.
Exposure to DEDTP has also been shown to lead to lower secretion of important cytokines like IL-2, IFN-γ, and IL-10 by human CD4+ T lymphocytes, which play a role in the regulation and signaling of the immune system.
Additionally, high levels of DEDTP and other OP metabolites have been linked to an increased prevalence of sleep disorders in adults, indicating a potential impact on neurological health. There is also evidence to suggest that exposure to DEDTP during pregnancy can negatively affect the neurodevelopmental outcomes of infants, such as expressive communication and fine motor performance.
How does DEDTP enter the body?
Diethyldithiophosphate (DEDTP) can enter the body through several routes, typically as a result of exposure to organophosphate pesticides, which are used in agriculture and pest control. Here are the common pathways of exposure:
- Inhalation: Breathing in air that contains pesticide particles or mist can lead to DEDTP entering the body. This is more likely in agricultural areas where pesticides are sprayed, or in spaces that have been recently treated for pest control.
- Dermal (skin) contact: Skin exposure can occur if you come into contact with surfaces or plants that have been treated with organophosphate pesticides. DEDTP can be absorbed through the skin, especially if the pesticides are not yet dry or if protective clothing is not worn during application.
- Ingestion: Eating food that has been treated with organophosphate pesticides and not properly washed can result in ingestion of DEDTP. This is one of the more common routes of exposure for the general population.
- Occupational exposure: People who work in agriculture, pest control, or in the manufacture of these pesticides are at a higher risk of exposure. Such individuals are advised to use personal protective equipment (PPE) to minimize the risk.
- Environmental exposure: Living near agricultural areas where pesticides are frequently used can increase the risk of environmental exposure to DEDTP.
To minimize the risk of DEDTP entering your body, it is important to follow safety guidelines when handling organophosphate pesticides, ensure proper washing of fruits and vegetables, and use appropriate protective gear if you work in environments where these substances are present. If there is a concern about potential exposure to DEDTP or similar compounds, it's advisable to consult with a healthcare provider or a professional specializing in environmental health or toxicology.
Potential treatment:
Since DEDTP is a metabolite of organophosphate pesticides, it would be important to stop exposure to the source of organophosphates. This could involve avoiding areas where these pesticides are used, changing dietary habits to reduce ingestion of contaminated food, or changing occupational practices if exposure is work-related.
If elevated DEDTP levels are detected, it is crucial to consult healthcare professionals who specialize in toxicology or occupational medicine. These specialists can provide guidance on the appropriate measures to take, including monitoring, health surveillance, and, if necessary, treatment for any health effects.
For someone with elevated levels of DEDTP, a doctor might also recommend certain detoxification methods, such as using certain supplements or therapies that support liver and kidney function, which are involved in metabolizing and excreting toxins. However, these methods should only be used under the guidance of a healthcare provider.
Sign up
Sign up now and create your account. Use code HEALTH10 for a 10% discount on any plan. Don't miss out!
Organize
Bring all results from any laboratories to your account. You can enter your tests yourself, or we'll be happy to organize your files—whether in PDF, JPEG, CSV, or even screenshots.
Learn and improve
Once your information is stored in your account, dive into a wealth of insights about your results. If you have any more questions, we are here to answer them.
Guiding our user for 10 years to promptly understand, track, and act on their laboratory results.
$15/month
for personal lab results
Cancel your subscription at any time.
$250/once
full premium version
$45/month
track your clients’ labs
Cancel your subscription at any time.
Guiding our user for 10 years to promptly understand, track, and act on their laboratory results.
Personal plans
track personal results
Professional Plan
track multiple client's results
$15/month
for personal lab results
$250/once
own it for life
$45/month
for health professionals
Complete Plan
Unlimited Plan
$15 per month
$250 full version
Are you a health professional?
Level up your lab report analysis with our Pro plan, built for health practitioners like you.
Health Business Account
$45/month
Cancel your subscription at any time.
Unlock additional Pro plans when you sign up.
Unlock Your Health Journey with Healthmatters.io! Ever wished for a one-stop digital health haven for all your lab tests? Look no further! Healthmatters.io is your personalized health dashboard, bringing together test reports from any lab. Say goodbye to scattered results—organize and centralize your lab data effortlessly. Dive into the details of each biomarker and gain insights into the meaning behind your medical test data.
Join the community of thousands who've transformed the way they understand their lab results. Experience the joy of having all your lab data neatly organized, regardless of where or when the tests were done.
For our professional users, Healthmatters.io is a game-changer. Revel in the intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history. It's not just a dashboard; it's your gateway to a smarter, more informed health journey!
Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we do talk about popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters. We can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
Still on the hunt for a specific biomarker? Just tell us, and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account!
There are two ways to add your test reports to your healthmatters.io account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."
Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.
For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you. We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.
Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.
Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.
For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.
Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.
Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.
The Unlimited plan is a one-time purchase for $250, and it covers your account for a lifetime with no additional payments.
For the Complete plan, the cost is $15 per month. You have the flexibility to cancel it anytime through your account settings, ensuring no further payments. To avoid charges, remember to cancel at least a day before the renewal date. Once canceled, the subscription remains active until the end of the current billing cycle.
Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.
You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.
Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.
Unlocking the insights from your lab tests has never been this intuitive! We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into a treasure trove of testing data.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
2. All Tests ViewGet a quick grasp of your test reports in minutes! Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.
3. Table View:For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.
Experience the power of clear, organized data visualization with Healthmatters.io — your key to understanding and taking charge of your health journey!
Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.
Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.
A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.
The professional or business account is designed for health professionals who wish to track and organize their clients' laboratory results.
To learn more about Healthmatters Pro, please refer to the professional page.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
2,2-bis(4-Chlorophenyl) acetic acid (DDA), 2-Hydroxyisobutyric Acid (2HIB), 4-Nonylphenol, Aflatoxin B1 (AFB1), Aflatoxin B2 (AFB2), Aflatoxin G2, Antimony, Atrazine mercapturate, Barium, Beryllium, Bisphenol A (BPA), Butylparaben, Cadmium, Cesium, Chaetoglobosin A (CHA), Citrinin (CTN), Diethyldithiophosphate (DEDTP), Dihydrocitrinone, Dimethyl phosphate (DMP), Gadolinium, GenX/HPFO-DA, Glyphosate, Mercury, Methylparaben, Mycophenolic Acid, N-Acetyl (2,Hydroxypropyl) Cysteine (NAHP), N-Acetyl (Propyl) Cysteine (NAPR), Ochratoxin A (OTA), Perchlorate (PERC), Perfluoroheptanoic acid (PFHpA), Perfluoropentanoic acid (PFPeA), Perfluoroundecanoic acid (PFUnA), Phenyl glyoxylic Acid (PGO), Thallium, Tungsten, Zearalenone (ZEN)
