Estrone is one of the three major naturally occurring estrogens, alongside estradiol and estriol.

Estrone, as a marker in a Human Urinary Metabolic Profile (HUMAP) panel for pre-menopausal women, offers valuable insights into estrogen metabolism and overall hormonal balance.

In pre-menopausal women, it plays a pivotal role in the menstrual cycle and overall reproductive health. Unlike estradiol, which is the predominant form of estrogen during the reproductive years, estrone becomes more significant after menopause. However, its levels and balance in pre-menopausal women are still crucial.

Produced by the ovaries, the estrone hormone is one of three types of estrogen, and it is one of the major hormones found in the bodies of postmenopausal women. While research into estrone function is still ongoing, since it is the least powerful of the three estrogen types, women should still understand this hormone and its known effects on the body.

- Weaker compared to Estradiol (Research says the estrogenic activity is about 4% of estradiol’s activity)

- Most abundant in menopause

- Made via aromatization in several tissues like fat and muscle

- Converts into estradiol (E2)

Estrone (E1) is also made by the ovary but in fat tissue in lesser quantities. While not as abundant in circulation as estradiol, estrone excess can still increase the risk for estrogen dominant cancers and estrogen dominant symptoms such as breast tenderness, heavy menstrual cycles, headaches, and erectile dysfunction and breast development in men just like estradiol. Estrone is commonly thought to be more abundant during menopause. 

Estradiol and estrone can interconvert into each other. 

Estrone Sulfate is a vital biomarker that plays a significant role in assessing hormonal health, particularly in women. Estrone sulfate is a conjugated form of estrone, one of the three main types of estrogen, and it serves as a major circulating estrogen in the bloodstream. It is primarily produced in the ovaries, placenta, and adipose tissue.

Testing of estrone sulfate levels is critical for understanding various health conditions, including menopausal status, ovarian function, and potential hormone-related disorders. In premenopausal women, estrone sulfate levels provide insights into ovarian function, whereas in postmenopausal women, these levels can help assess the risk of estrogen-related conditions such as osteoporosis or cardiovascular disease.

There are three types of estrogen: estradiol, estriol, and estrone. Estradiol is the primary female sex hormone. Estriol and estrone are minor female sex hormones. Estriol is nearly undetectable in women who aren’t pregnant.

Estrone (E1) is a steroid, a weak estrogen, and a minor female sex hormone. Estrone is one of three major endogenous estrogens, the others being estradiol and estriol. Like the other estrogens, estrone is synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Estrone can be converted into estradiol and serves mainly as a precursor or metabolic intermediate of estradiol. In addition, an increase in the ratio of estrone to estradiol may be useful in assessing menopause in women.

Estrone (E1) is a steroid, a weak estrogen, and a minor female sex hormone. Estrone is one of three major endogenous estrogens, the others being estradiol and estriol. Like the other estrogens, estrone is synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Estrone can be converted into estradiol and serves mainly as a precursor or metabolic intermediate of estradiol. In addition, an increase in the ratio of estrone to estradiol may be useful in assessing menopause in women.

Quantitation of alcohol level for medical or legal purposes; test unconscious patients; used to diagnose alcohol intoxication and determine appropriate therapy; detect alcoholism and to monitor ethanol treatment for methanol intoxication. Must be tested as possible cause of coma of unknown etiology since alcohol intoxication may mimic diabetic coma, cerebral trauma, and drug overdose.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation. Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation. Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation.

Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation. Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation. Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation. Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is an intermediary metabolite in the serine-to-choline sequence. It can be used to synthesize phosphatidylethanolamine (PE), a very important membrane phospholipid. Ethanolamine is not only a precursor, but also a breakdown product of PE. Ethanolamine is abundant in both intestinal and bacterial cell membranes. It plays a significant role in the renewal and proliferation of intestinal cells and intestinal inflammation. Also, since ethanolamine plays a structural role in skeletal muscle cell membranes, some evidence suggests it may be a marker of skeletal muscle turnover.

Ethanolamine is a metabolite of the nonessential amino acid serine. In the presence of adequate levels of functional B-6 (P-5-P) serine is enzymatically converted to ethanolamine.

Ethanolamine is a metabolite of the nonessential amino acid serine. In the presence of adequate levels of functional B-6 (P-5-P) serine is enzymatically converted to ethanolamine.

Ethanolamine, Plasma is a marker measured in an Amino Acid Profile, Quantitative (Plasma) panel, which plays an important role in various bodily functions. Ethanolamine is a key component of phospholipids, which are essential building blocks of cell membranes. This compound is involved in the synthesis of phosphatidylethanolamine, a crucial phospholipid that helps maintain the structural integrity and fluidity of cell membranes. Beyond its structural role, ethanolamine is also involved in cell signaling and neurotransmission, particularly in the central nervous system. It serves as a precursor for the synthesis of acetylcholine, a vital neurotransmitter that affects muscle contraction, memory, and learning. Normal levels of ethanolamine in the plasma indicate proper cellular function and membrane stability.

Ethinyl estradiol is an estrogen receptor agonist commonly used in combined oral contraceptives. It is a synthetic derivative of estradiol. In the liver it stimulates the synthesis of SHBG, increasing SHBG levels by 2- to 4-fold in women, which has the effect of binding more circulating testosterone and reducing free testosterone concentrations by 40-80%. The suppression of free testosterone levels may impact female sexual desire.