Amino Acids 40 Profile
Plasma
Performed by: Genova Diagnostics
This test determines essential amino acid imbalances that affect both physical and mental function
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Biomarkers included in this panel:
It is a component of the dietary peptide anserine. Anserine is beta-alanyl-1-methyl-L-histidine, and it is known to come from chicken, turkey, duck, rabbit, tuna and salmon.
Learn more3-Methylhistidine is an amino acid which is excreted in human urine. The measurement of 3-methylhistidine provides an index of the rate of muscle protein breakdown. 3-Methylhistidine is a biomarker for meat consumption, especially chicken. It is a
Learn moreAlanine is a non-essential amino acid and helps the body convert the simple sugar glucose into energy and eliminate excess toxins from the liver.
Learn moreAlpha-Amino-n-butyric acid (A-ANB/α-Amino-N-butyric acid) is an intermediate occurring in the catabolism of two essential amino acids, methionine and threonine.
Learn moreAlpha-aminoadipic acid (a-Aminoadipic acid) is an intermediary metabolite of lysine (primarily) and of tryptophan.
Learn moreAlcohol consumption can result in elevations of the plasma Alpha-ANB/Leucine ratio. But to see this biomarker as a conclusive marker for alcoholism is not proven. The increase in the plasma Alpha-ANB/Leucine ratio does not appear to be specific
Learn moreAnserine is part of a group of Beta-Amino Acids and Derivatives. Anserine is beta-alanyl-1-methyl-L-histidine, and it is known to come from chicken, turkey, duck, rabbit, tuna and salmon.
Learn moreArginine is a conditionally essential amino acid that is critical for your cardiovascular health and detoxification functions. The amino acid, arginine, is used to make the powerful blood vessel regulator, nitric oxide. Nitric oxide acts to lower blo
Learn moreAsparagine is a protein amino acid. It is non-essential in humans, meaning the body can synthesize it. Asparagine is synthesized from aspartate and glutamine. Asparagine has three major functions: incorporation into amino acid sequences of p
Learn moreAspartic acid is a nonessential protein amino acid. Aspartic Acid, also known as aspartate, is an excitatory neurotransmitter in the brainstem and spinal cord. Aspartic acid is the excitatory counterpart to glycine, an inhibitory neurotransmitter.
Learn moreβ-alanine is a breakdown product of carnosine and anserine, which are dipeptides from meat consumption. Although β-alanine’s properties are limited, its relationship to carnosine makes it important. Both have antioxidant properties. C
Learn moreBeta-aminoisobutyric acid (BAIB) is an amino acid end product of the pyrimidine metabolism. It is excreted in small quantities into the urine in almost all human beings. Thymine, released when RNA and DNA are degraded, enters a catabolic pathway that
Learn moreCarnosine is a dietary peptide related marker that consists of histidine and beta-alanine. Carnosine is an incompletely digested peptide that is derived primarily from beef and pork.
Learn moreThe amino acid citrulline gets its name from its high concentration in the watermelon Citrullus vulgaris. In human kidneys, citrulline and aspartic acid are united by argininosuccinate synthetase (ASS) to produce arginosuccinate. The degrad
Learn moreCystathionine is an intermediary metabolite that is formed in the sequential enzymatic conversion of methionine to cysteine. Cystathionine is normally detected at very low levels in plasma. It is found between homocysteine an
Learn moreCystine is the oxidized disulfide form of cysteine (Cys) and is the predominant form of cysteine in the blood due to its greater relative stability. Cystine is derived from dietary protein and, end formed endogenously from cysteine.
Learn moreEthanolamine is a metabolite of the nonessential amino acid serine. In the presence of adequate levels of functional B-6 (P-5-P) serine is enzymatically converted to ethanolamine.
Learn moreGABA is a neurotransmitter that inhibits nervous system activity, producing a relaxation effect.
Learn moreGlutamic acid (or Glutamate) is a major mediator of excitatory signals in the brain and is involved in most aspects of normal brain function including cognition, memory and learning.
Learn moreThe Glutamic Acid/Glutamine Ratio is used to identify specimen handling issues that cause spontaneous degradation of glutamine to glutamate, and can reveal the origin of difficulty maintaining systemic pH balance.
Learn moreGlutamine is the most abundant amino acid in the blood and is an important source of energy for many tissues in the body. It is derived from the amino acids histidine and glutamic acid.
Learn moreGlycine is an amino acid with various important functions within your body, including detoxification, DNA formation, the synthesis of hemoglobin, and as a part of brain neurotransmission pathways. Glycine and serine are interchangeable.
Learn moreHistidine is the amino acid most necessary during stress. Amino acids are the building blocks of protein in our bodies.
Learn moreHomocysteine is a sulphur-containing amino acid and is an intermediate metabolite of methionine metabolism. Homocysteine is a well-known cardiovascular disease risk factor.
Learn moreHomocystine is a common amino acid in your blood. You get it mostly from eating meat. High levels of it are linked to early development of heart disease.
Learn moreHydroxylysine is an amino acid related to collagen. What is collagen? Collagen is the most abundant protein in your body. It is the major component of connective tissues that make up several body parts, including tendons, ligamen
Learn moreHydroxyproline is a collagen related amino acid. Hydroxyproline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver. Hydroxyproline is necessary for the construction of the body’s major structur
Learn moreThe Hydroxyproline to Proline Ratio describes the relationship between Proline and Hydroxyproline and can be looked at in relation to your collagen metabolism.
Learn moreIsoleucine is one of the three branched-chain amino acids (BCAAs) alongside both leucine and valine. Isoleucine is a common component of proteins, peptides and hormones. Leucine is catabolized as a source of carbon for ene
Learn moreLeucine, together with isoleucine and valine, are essential amino acids that are referred to as branched-chain amino acids (BCAAs). Leucine is nutritionally essential and is required for formation of body proteins, enzymes and
Learn moreLysine is found in great quantities in muscle tissues, stimulates calcium absorption, carnitine synthesis, and growth and repair of muscle tissue.
Learn moreMethionine is an essential amino acid, meaning we need to get it from our diet as our body does not produce it. Methionine is a unique sulfur-containing amino acid that can be used to build proteins and produce many molecules in the body.
Learn moreOrnithine is a urea cycle metabolite. Ornithine can stimulate the release of growth hormone. Growth hormone is necessary for tissue repair and growth. Growth hormone is often low in patients with fibromyalgia.
Learn morePhenylalanine is a precursor for the amino acid tyrosine, which is essential for making neurotransmitters (e.g. epinephrine, norepinephrine, dopamine) and thyroid hormone. Neurotransmitters are the chemicals that communicate
Learn moreThe Phenylalanine/Tyrosine Ratio evaluates the body’s ability to convert phenylalanine to tyrosine; Conversion enzyme requires tetrahydrobiopterin (BH4), niacin (B3), and iron as cofactors.
Learn morePhosphoethanolamine together with Ethanolamine and Phosphoserine are amino acids that are closely related structurally and they share principal roles in phospholipid metabolism. Phospholipids are a class of lipids that are important component
Learn morePhosphoserine is a product of glycolysis and is formed by amino group transfer from glutamic acid to phosphohydroxypyruvic acid.
Learn moreProline is a nonessential amino acid, which means that it is manufactured from other amino acids in the liver; it does not have to be obtained directly through the diet. Proline is the precursor to hydroxyproline, which is a major amino acid
Learn moreSarcosine is also known as N-methylglycine. It is an intermediate and byproduct in the glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generate
Learn moreSerine can be used as an energy source. Formed from threonine and phosphoserine (requiring B6, manganese, and magnesium), serine is necessary for the biosynthesis of acetylcholine, a neurotransmitter used in memory function.
Learn moreTaurine is a sulfur-containing amino acid required for bile formation.
Learn moreThreonine is an essential amino acid, i.e., it is vital for your health, but it cannot be synthesized by your body and therefore has to be obtained from a diet.
Learn moreTryptophan is an essential amino acid required for the production of the neurotransmitter serotonin.
Learn moreTryptophan is an essential amino acid, a subunit in protein molecules and a precursor to serotonin. The brain uses tryptophan to produce serotonin, a neurotransmitter largely responsible for feelings of happiness and well-bei
Learn moreTyrosin is the non-essential amino acid precursor for dopamine, norepinephrine and epinephrine. Tyrosine hydroxylase converts tyrosine into the dopamine precursor L-DOPA; BH4, Vitamin D and iron are cofactors for that enzymatic activity.
Learn moreValine, together with Isoleucine and Leucine are essential amino acids and are collectively referred to as branched-chain amino acids (BCAAs).
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