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Homocysteine

Serum

Metabolic Health

Optimal range:   0 - 14.5 µmol/L , 0.00 - 14.50 umol/L

Homocysteine is an amino acid that requires vitamin B12 and folate to be used by our bodies. As such, homocysteine blood tests are often ordered to identify vitamin B12 / folate deficiency.

Rarely, an abnormally high level of homocysteine indicates a rare genetic disorder called homocystinuria.

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HOMOCYSTEINE

Methionine Metabolism Profile (NutriPATH), NutriPATH

Optimal range:   0 - 0 umol/L

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Homocysteine (Genova)

Amino Acids 40 Profile, Genova Diagnostics

Optimal range:   3 - 14 nmol/ML

Homocysteine is a sulphur-containing amino acid and is an intermediate metabolite of methionine metabolism. Homocysteine is a well-known cardiovascular disease risk factor.

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Homocystine

Amino Acids test [Great Plains Laboratory / Doctor's Data], Doctor's Data

Optimal range:   0 - 1 qM/g creatinine

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Homocystine

Amino Acid Profile, Qn (Plasma), LabCorp

Optimal range:   0 - 0.2 umol/L

Homocystine is a common amino acid in your blood. You get it mostly from eating meat. High levels of it are linked to early development of heart disease.

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Homocystine

Urine

Amino Acids; Urine 24-hour (Doctor's Data), Doctor's Data

Optimal range:   0 - 1.2 qmol/24 hours

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Homocystine

Amino Acid Analysis, Quest Diagnostics

Optimal range:   0 - 1 umol/L

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Homocystine

Urine

Amino Acid Profile, Qn (Urine), LabCorp

Optimal range:   0.3 - 1.4 umol/g Cr

Homocystine is the oxidized form of homocysteine. A substance is oxidized when it undergoes the process of oxidation. I.e the addition of oxygen or any electronegative elements or the removal of hydrogen or any electropositive element.

Homocystine is a dipeptide consisting of two homocysteine molecules joined by a disulfide bondA dipeptide is a molecule that consists of two amino acids joined together by a peptide bond. 

Homocystine occurs only transiently before being reduced to homocysteine and converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocystine and homocysteine-cysteine mixed disulfides account for >98% of total homocysteine in plasma from healthy individuals.

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Homocystine

Urinary Amino Acids (Synlab), SYNLAB

Optimal range:   0 - 0 mmol/mol creatinine

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HOMOCYSTINE

Urine

Amino Acid Analysis, LC/MS, Quest Diagnostics

Optimal range:   0 - 1 mmol/mol creatinine

Homocystine is the oxidized form of homocysteine. A substance is oxidized when it undergoes the process of oxidation. I.e the addition of oxygen or any electronegative elements or the removal of hydrogen or any electropositive element.

Homocystine is a dipeptide consisting of two homocysteine molecules joined by a disulfide bond. A dipeptide is a molecule that consists of two amino acids joined together by a peptide bond. 

Homocystine occurs only transiently before being reduced to homocysteine and converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocystine and homocysteine-cysteine mixed disulfides account for >98% of total homocysteine in plasma from healthy individuals.

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Homocystine

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   0 - 2.6 nmol/mg Creatinine

→ Plasma homocystine is higher in those with cystathionine-beta-synthase deficiency.

→ Plasma homocystine, as well as taurine, were significantly lower in insufficient methotrexate therapy responders.

→ Homocystine is an oxidized disulfide form of homocysteine, which gets readily converted to cystathionine.

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Homocystine (Genova)

Amino Acids 40 Profile, Genova Diagnostics

Optimal range:   0 - 0.6 µmol/L

Homocystine is a common amino acid in your blood. You get it mostly from eating meat. High levels of it are linked to early development of heart disease.

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Homocystine (Plasma)

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   0 - 2.2 nmol/ML

Homocystine is a common amino acid in your blood. You get it mostly from eating meat. High levels of it are linked to early development of heart disease.

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Homogeneous Pattern

Serum

ANA 12 Plus Profile (RDL), LabCorp

Reference range:   Low, High, Borderline

The Homogeneous pattern observed in an Antinuclear Antibody (ANA) test is a specific type of result that indicates the presence of antibodies in the blood that are reacting against components in the cell nucleus. This pattern is termed 'homogeneous' because the antibodies produce a uniform, diffuse staining of the entire nucleus in a cell. The ANA test is commonly used in the diagnosis and management of autoimmune diseases, where the body's immune system mistakenly attacks its own cells. A homogeneous pattern is often associated with systemic lupus erythematosus (SLE), a complex autoimmune disorder, but it can also be seen in other conditions such as rheumatoid arthritis, Sjogren's syndrome, and mixed connective tissue disease. However, it's important to note that ANA patterns, including the homogeneous pattern, are not exclusive to any single disease. The presence of this pattern requires careful interpretation by a healthcare professional in the context of the patient's symptoms, clinical history, and other laboratory findings. Additionally, a small percentage of healthy individuals can have a positive ANA test, including a homogeneous pattern, without any underlying autoimmune disease. Therefore, while the homogeneous pattern provides valuable diagnostic clues, it is part of a larger puzzle in understanding and managing autoimmune disorders.

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Homogentisic

Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 2 mmol/mol creatinine

Homogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA). 

Elevated in the genetic disease homogentisic aciduria (alkaptonuria).

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Homogentisic

Organic Acids, Comprehensive, Quantitative, Quest Diagnostics

Optimal range:   0 - 0 mmol/mol creatinine

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Homogentisic (Males Age 13 and Over)

Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 2 mmol/mol creatinine

Homogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA). 

Elevated in the genetic disease homogentisic aciduria (alkaptonuria).

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Homogentisic (Males Under Age 13)

Organic Acids Test (OAT) - Nutritional and Metabolic Profile, Mosaic Diagnostics

Optimal range:   0 - 2 mmol/mol creatinine

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Homogentisic Acid

OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   0 - 153.7 nmol/mg Creatinine

Homogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA). 

Elevated in the genetic disease homogentisic aciduria (alkaptonuria).

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Homogentisic Acid

Metabolic Analysis Markers (Urine)

Optimal range:   0 - 19 mmol/mol creatinine

Homogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA).

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