Organic Acids Test (OAT) - Nutritional and Metabolic Profile

Urine

Performed by: Mosaic Diagnostics

Biomarkers included in this panel:

2-Hydroxybutyric

What is 2-Hydroxybutyric acid? 2-Hydroxybutyric acid (aka α-Hydroxybutyrate) is a by-product of glutathione production. Levels of 2-Hydroxybutyric acid in the urine may reflect levels of glutathione production. What is Glutathione? Glu

Learn more

2-Hydroxybutyric (Males Age 13 and Over)

What is 2-Hydroxybutyric acid? 2-Hydroxybutyric acid (aka α-Hydroxybutyrate) is a by-product of glutathione production. Levels of 2-Hydroxybutyric acid in the urine may reflect levels of glutathione production. What is Glutathione? Glu

Learn more

2-Hydroxybutyric (Males Under Age 13)

What is 2-Hydroxybutyric acid? 2-Hydroxybutyric acid (aka α-Hydroxybutyrate) is a by-product of glutathione production. Levels of 2-Hydroxybutyric acid in the urine may reflect levels of glutathione production. What is Glutathione? Glu

Learn more

2-Hydroxyhippuric

2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.

Learn more

2-Hydroxyhippuric (Females Under Age 13)

2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.

Learn more

2-Hydroxyhippuric (Males Age 13 and Over)

2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.

Learn more

2-Hydroxyhippuric (Males Under Age 13)

2-Hydroxyhippuric acid is a conjugate of hydroxybenzoic acid (salicylic acid) and glycine.

Learn more

2-Hydroxyisocaproic

2-Hydroxyisocaproic acid (aka Leucic acid / α-hydroxyisocaproic acid / HICA) is a metabolite of the branched-chain amino acid leucine.

Learn more

2-Hydroxyisocaproic (Males Age 13 and Over)

2-Hydroxyisocaproic acid (aka Leucic acid / α-hydroxyisocaproic acid / HICA) is a metabolite of the branched-chain amino acid leucine.

Learn more

2-Hydroxyisocaproic (Males Under Age 13)

2-Hydroxyisovaleric

2-Hydroxyisovaleric acid (aka 2-Hydroxy-3-methylbutyric acid) is a branched-chain amino acid metabolite.

Learn more

2-Hydroxyisovaleric (Males Age 13 and Over)

2-Hydroxyisovaleric acid (aka 2-Hydroxy-3-methylbutyric acid) is a branched-chain amino acid metabolite.

Learn more

2-Hydroxyisovaleric (Males Under Age 13)

2-Hydroxyisovaleric acid (aka 2-Hydroxy-3-methylbutyric acid) is a branched-chain amino acid metabolite.

Learn more

2-Hydroxyphenylacetic

The metabolite of phenylalanine via phenyl pyruvate.

Learn more

2-Hydroxyphenylacetic (Males Age 13 and Over)

The metabolite of phenylalanine via phenyl pyruvate.

Learn more

2-Hydroxyphenylacetic (Males Under Age 13)

The metabolite of phenylalanine via phenyl pyruvate.

Learn more

2-Oxo-4-methiolbutyric

2-Oxo-4-methylthiobutanoic acid, also known as 4-(methylsulfanyl)-2-oxobutanoate or 2-keto-4-methylthiobutyrate, belongs to the class of organic compounds known as thia fatty acids. Thia substituted fatty acids are saturated 

Learn more

2-Oxo-4-methiolbutyric (Males Age 13 and Over)

2-Oxo-4-methylthiobutanoic acid, also known as 4-(methylsulfanyl)-2-oxobutanoate or 2-keto-4-methylthiobutyrate, belongs to the class of organic compounds known as thia fatty acids. Thia substituted fatty acids are saturated 

Learn more

2-Oxo-4-methiolbutyric (Males Under Age 13)

2-Oxoglutaric

2-Oxoglutaric acid is an organic acid that is important for the proper metabolism of all essential amino acids. It is formed in the Krebs cycle, the energy-producing process that occurs in most body cells.

Learn more

2-Oxoglutaric (Males Age 13 and Over)

2-Oxoglutaric acid is an organic acid that is important for the proper metabolism of all essential amino acids. It is formed in the Krebs cycle, the energy-producing process that occurs in most body cells.

Learn more

2-Oxoglutaric (Males Under Age 13)

2-Oxoisocaproic

2-Oxoisocaproic acid (also known as Ketoleucine) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 2-Oxoisocaproic acid is both a neurotoxin and a metabotoxin.

Learn more

2-Oxoisocaproic (Males Age 13 and Over)

2-Oxoisocaproic acid (also known as Ketoleucine) is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 2-Oxoisocaproic acid is both a neurotoxin and a metabotoxin.

Learn more

2-Oxoisocaproic (Males Under Age 13)

2-Oxoisovaleric

2-Oxoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids (=BCAA). 2-Oxoisovaleric acid is a neurotoxin, an acidogen, and a metabotoxin. 

Learn more

2-Oxoisovaleric (Males Age 13 and Over)

2-Oxoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids (=BCAA). 2-Oxoisovaleric acid is a neurotoxin, an acidogen, and a metabotoxin. 

Learn more

2-Oxoisovaleric (Males Under Age 13)

3-Hydroxy-3-methylglutaric (HMG)

- A precursor in the production of cholesterol in both humans and yeast. - Elevated levels may also indicate decreased CoQ10 synthesis. - Moderate increases are probably due to yeast overgrowth of the GI tract and might also implicate yeast ove

Learn more

3-Hydroxy-3-methylglutaric (Males Age 13 and Over)

- A precursor in the production of cholesterol in both humans and yeast. - Elevated levels may also indicate decreased CoQ10 synthesis. - Moderate increases are probably due to yeast overgrowth of the GI tract and might also implicate yeast ove

Learn more

3-Hydroxy-3-methylglutaric (Males Under Age 13)

3-Hydroxybutyric

3-Hydroxybutyric acid is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis. This acid is metabolized by 3-hydroxybutyrate dehydrogenase. The enzyme f

Learn more

3-Hydroxybutyric (Males Age 13 and Over)

3-Hydroxybutyric acid is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis. This acid is metabolized by 3-hydroxybutyrate dehydrogenase. The enzyme f

Learn more

3-Hydroxybutyric (Males Under Age 13)

3-Hydroxybutyric acid is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis. This acid is metabolized by 3-hydroxybutyrate dehydrogenase. The enzyme f

Learn more

3-Hydroxyglutaric

3-Hydroxyglutaric is a marker for glutaryl CoA dehydrogenase deficiency.

Learn more

3-Hydroxyglutaric (Males Age 13 and Over)

3-Hydroxyglutaric is a marker for glutaryl CoA dehydrogenase deficiency.

Learn more

3-Hydroxyglutaric (Males Under Age 13)

3-Indoleacetic

3-Indoleacetic is a Tryptophan byproduct of Clostria: C. stricklandii, C. litusburense, C. subterminale, and C. putrefaciens.

Learn more

3-Indoleacetic (Males Age 13 and Over)

3-Indoleacetic is a Tryptophan byproduct of Clostria: C. stricklandii, C. litusburense, C. subterminale, and C. putrefaciens.

Learn more

3-Indoleacetic (Males Under Age 13)

3-Methyl-2-oxovaleric

3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.  Moderate increase may result from lactic acidosis, episodic ketosis, or thiamine/lipoic acid deficiency. Significan

Learn more

3-Methyl-2-oxovaleric (Males Age 13 and Over)

3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.  Moderate increase may result from lactic acidosis, episodic ketosis, or thiamine/lipoic acid deficiency. Significan

Learn more

3-Methyl-2-oxovaleric (Males Under Age 13)

3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.  Moderate increase may result from lactic acidosis, episodic ketosis, or thiamine/lipoic acid deficiency. Significan

Learn more

3-Methylglutaconic

The marker, 3-methylglutaconic acid in high values indicates a reduced ability to metabolize the amino acid, leucine. This abnormality is found in the genetic disease, methylglutaconic aciduria and in mitochondrial disorders.

Learn more

3-Methylglutaconic (Males Age 13 and Over)

The marker, 3-methylglutaconic acid in high values indicates a reduced ability to metabolize the amino acid, leucine. This abnormality is found in the genetic disease, methylglutaconic aciduria and in mitochondrial disorders.

Learn more

3-Methylglutaconic (Males Under Age 13)

3-Methylglutaric

3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.

Learn more

3-Methylglutaric (Females Under Age 13)

3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.

Learn more

3-Methylglutaric (Males Age 13 and Over)

3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.

Learn more

3-Methylglutaric (Males Under Age 13)

3-methylglutaric acid is an organic acid classically associated with two distinct leucine pathway enzyme deficiencies.

Learn more

3-Oxoglutaric

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

Learn more

3-Oxoglutaric (Males Age 13 and Over)

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

Learn more

3-Oxoglutaric (Males Under Age 13)

3-Oxoglutaric indicates yeast overgrowth in the gastrointestinal tract. 

Learn more

4-Cresol

4-Cresol has been used as a specific marker for Clostridium difficile.

Learn more

4-Cresol (Males Age 13 and Over)

4-Cresol has been used as a specific marker for Clostridium difficile.

Learn more

4-Cresol (Males Under Age 13)

4-Hydroxybenzoic

4-Hydroxybenzoic Acid is a marker for intestinal dysbiosis.

Learn more

4-Hydroxybenzoic (Males Age 13 and Over)

4-Hydroxybenzoic Acid is a marker for intestinal dysbiosis.

Learn more

4-Hydroxybenzoic (Males Under Age 13)

4-Hydroxybenzoic Acid is a marker for intestinal dysbiosis.

Learn more

4-Hydroxybutyric

A moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria

Learn more

4-Hydroxybutyric (Females Under Age 13)

A moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria

Learn more

4-Hydroxybutyric (Males Age 13 and Over)

A moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria

Learn more

4-Hydroxybutyric (Males Under Age 13)

A moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplements containing 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may indicate the genetic disorder 3-methylglutaconic aciduria

Learn more

4-Hydroxyhippuric

4-Hydroxyhippuric is a glycine conjugate of 4-hydroxybenzoic acid, the paraben metabolite.

Learn more

4-Hydroxyhippuric (Males Age 13 and Over)

4-Hydroxyhippuric is a glycine conjugate of 4-hydroxybenzoic acid, the paraben metabolite.

Learn more

4-Hydroxyhippuric (Males Under Age 13)

4-Hydroxyhippuric is a glycine conjugate of 4-hydroxybenzoic acid, the paraben metabolite.

Learn more

4-Hydroxyphenylacetic

A tyrosine metabolic product of GI bacteria.

Learn more

4-Hydroxyphenylacetic (Females Under Age 13)

A tyrosine metabolic product of GI bacteria.

Learn more

4-Hydroxyphenylacetic (Males Age 13 and Over)

A tyrosine metabolic product of GI bacteria.

Learn more

4-Hydroxyphenylacetic (Males Under Age 13)

A tyrosine metabolic product of GI bacteria.

Learn more

4-Hydroxyphenyllactic

4-hydroxyphenyllactate is present in relatively higher concentrations in the cerebrospinal fluid and urine of patients with phenylketonuria (PKU) and tyrosinemia.

Learn more

4-Hydroxyphenyllactic (Males Age 13 and Over)

4-hydroxyphenyllactate is present in relatively higher concentrations in the cerebrospinal fluid and urine of patients with phenylketonuria (PKU) and tyrosinemia.

Learn more

4-Hydroxyphenyllactic (Males Under Age 13)

5-Hydroxyindoleacetic (5-HIAA)

5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin is a hormone found at high levels in many body tissues. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels

Learn more

5-Hydroxyindoleacetic (5-HIAA) (Males Age 13 and Over)

5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin is a hormone found at high levels in many body tissues. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels

Learn more

5-Hydroxyindoleacetic (5-HIAA) (Males Under Age 13)

5-Hydroxymethyl-2-furoic

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

Learn more

5-Hydroxymethyl-2-furoic (Males Age 13 and Over)

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

Learn more

5-Hydroxymethyl-2-furoic (Males Under Age 13)

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth levels.

Learn more

Acetoacetic

Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.

Learn more

Acetoacetic (Males Age 13 and Over)

Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.

Learn more

Acetoacetic (Males Under Age 13)

Acetoacetic acid (=acetoacetate) is a ketone body and a weak Beta-keto acid produced from acetyl-CoA in the mitochondrial matrix of hepatocytes.

Learn more

Aconitic

Elevated in mitochrondrial disorders. Aconitase metabolizes citric and aconitic acids, and is dependent on glutathione.

Learn more

Aconitic (Males Age 13 and Over)

Elevated in mitochrondrial disorders. Aconitase metabolizes citric and aconitic acids, and is dependent on glutathione.

Learn more

Aconitic (Males Under Age 13)

Elevated in mitochrondrial disorders. Aconitase metabolizes citric and aconitic acids, and is dependent on glutathione.

Learn more

Adipic

Adipic Acid, together with Suberate and Ethylmalonate are all functional markers for deficiency of carnitine.

Learn more

Adipic (Males Age 13 and Over)

Adipic Acid, together with Suberate and Ethylmalonate are all functional markers for deficiency of carnitine.

Learn more

Adipic (Males Under Age 13)

Adipic Acid, together with Suberate and Ethylmalonate are all functional markers for deficiency of carnitine.

Learn more

Arabinose

Breakdown product of hyaluronic acid; also found in certain foods.

Learn more

Arabinose (Females Under Age 13)

Produced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation of the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose. Antifungal treatment and high-potency, multi-s

Learn more

Arabinose (Males Age 13 and Over)

Breakdown product of hyaluronic acid; also found in certain foods.

Learn more

Arabinose (Males Under Age 13)

Produced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation of the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose. Antifungal treatment and high-potency, multi-s

Learn more

Ascorbic

Ascorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibro

Learn more

Ascorbic (Males Age 13 and Over)

Ascorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibro

Learn more

Ascorbic (Males Under Age 13)

Ascorbic Acid is a natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibro

Learn more

Carboxycitric

Carboxycitric is a metabolite of yeast/fungi and general indicator of gastrointestinal dysbiosis. Elevated yeast/fungal metabolites indicate overgrowth in the GI tract.

Learn more

Carboxycitric (Males Age 13 and Over)

Carboxycitric is a metabolite of yeast/fungi and general indicator of gastrointestinal dysbiosis. Elevated yeast/fungal metabolites indicate overgrowth in the GI tract.

Learn more

Carboxycitric (Males Under Age 13)

Citramalic

Metabolite of yeast or anaerobic bacteria, including Clostridia.

Learn more

Citramalic (Males Age 13 and Over)

Metabolite of yeast or anaerobic bacteria, including Clostridia.

Learn more

Citramalic (Males Under Age 13)

Citric

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

Learn more

Citric (Males Age 13 and Over)

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

Learn more

Citric (Males Under Age 13)

Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells. 

Learn more

DHPPA (Beneficial Bacteria)

Produced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.

Learn more

DHPPA (Beneficial Bacteria) (Males Age 13 and Over)

Produced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.

Learn more

DHPPA (Beneficial Bacteria) (Males Under Age 13)

Produced when Clostridia acts upon unabsorbed tryptophan, tyrosine or phenylalanine.

Learn more

Dihydroxyphenylacetic (DOPAC)

HVA and DOPAC are the major metabolites of dopamine.

Learn more

Dihydroxyphenylacetic (DOPAC) (Females Under Age 13)

HVA and DOPAC are the major metabolites of dopamine.

Learn more

Dihydroxyphenylacetic (DOPAC) (Males Age 13 and Over)

HVA and DOPAC are the major metabolites of dopamine.

Learn more

Dihydroxyphenylacetic (DOPAC) (Males Under Age 13)

HVA and DOPAC are the major metabolites of dopamine.

Learn more

Ethylmalonic

Ethylmalonate, together with Adipate and Suberate, gives information about your ability to process fatty acids.

Learn more

Ethylmalonic (Males Age 13 and Over)

Ethylmalonic (Males Under Age 13)

Fumaric

Fumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.

Learn more

Fumaric (Males Age 13 and Over)

Fumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.

Learn more

Fumaric (Males Under Age 13)

Fumarate (together with Succinate and Malate) is used in the body’s metabolic pathway that generates cellular energy – the Citric Acid Cycle.

Learn more

Furan-2,5-dicarboxylic

Furan 2,5-dicarboxylic is a byproduct of Aspergillus and other fungal species.

Learn more

Furan-2,5-dicarboxylic (Males Age 13 and Over)

Furan 2,5-dicarboxylic is a byproduct of Aspergillus and other fungal species.

Learn more

Furan-2,5-dicarboxylic (Males Under Age 13)

Furancarbonylglycine

Furancarbonylglycine is a metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

Learn more

Furancarbonylglycine (Females Under Age 13)

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.

Learn more

Furancarbonylglycine (Males Age 13 and Over)

Furancarbonylglycine is a metabolite produced by Aspergillus and possibly other fungal species in the GI tract.

Learn more

Furancarbonylglycine (Males Under Age 13)

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription or natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.

Learn more

Glutaric

Glutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.

Learn more

Glutaric (Females Under Age 13)

Glutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.

Learn more

Glutaric (Males Age 13 and Over)

Glutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.

Learn more

Glutaric (Males Under Age 13)

Glutaric acid is made from lysine & tryptophan via alphaketo-adipic acid. - Elevated in the genetic diseases glutaric academia types I and II. - Moderate increases may be due to deficiencies in riboflavin and coenzyme Q10, or celiac disease.

Learn more

Glyceric

The organic acids test by Great Plains Laboratory measures a few oxalate metabolites which can determine if someone has high oxalate levels. These include oxalic, glycolic, and glyceric. In humans and in yeast, glyoxalate is the parent compound th

Learn more

Glyceric (Males Age 13 and Over)

Normal values rule out genetic causes of significantly elevated urinary oxalic acid.

Learn more

Glyceric (Males Under Age 13)

Normal values rule out genetic causes of significantly elevated urinary oxalic acid.

Learn more

Glycolic

Indicator of genetic disease of oxalate metabolism called Hyperoxaluria type I due to a deficiency in the enzyme activity of alanine glyoxylate amino transferase (AGT).

Learn more

Glycolic (Males Age 13 and Over)

Indicator of genetic disease of oxalate metabolism called Hyperoxaluria type I due to a deficiency in the enzyme activity of alanine glyoxylate amino transferase (AGT).

Learn more

Glycolic (Males Under Age 13)

Hippuric

Hippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic aci

Learn more

Hippuric (Females Under Age 13)

Hippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic aci

Learn more

Hippuric (Males Age 13 and Over)

Hippuric acid is a conjugate (=a compound formed by the joining of two or more compounds) of glycine and benzoic acid formed in the liver. Most hippuric acid in urine is derived from microbial breakdown of chlorogenic acid to benzoic aci

Learn more

Hippuric (Males Under Age 13)

Homogentisic

Homogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA).  Elevated in the genetic disease homogentisic aciduria (alkaptonuria).

Learn more

Homogentisic (Males Age 13 and Over)

Homogentisic acid is a breakdown product of 4-Hydroxyphenylpyruvic Acid (4-HPPA).  Elevated in the genetic disease homogentisic aciduria (alkaptonuria).

Learn more

Homogentisic (Males Under Age 13)

Homovanillic (HVA)

Homovanillate (aka Homovanillic Acid) is a dopamine metabolite. Homovanillate and Vanilmandelate are breakdown products from neurotransmitters involved in hormone and nerve impulse transmission, called catecholamines.

Learn more

Homovanillic (HVA) (Males Age 13 and Over)

Homovanillate (aka Homovanillic Acid) is a dopamine metabolite. Homovanillate and Vanilmandelate are breakdown products from neurotransmitters involved in hormone and nerve impulse transmission, called catecholamines.

Learn more

Homovanillic (HVA) (Males Under Age 13)

HPHPA

HPHPA is a clostridia metabolite and dysbiosis marker and stands for 3-(3-hydroxyphenyl)-3-hydroxypropionic acid.

Learn more

HPHPA (Males Age 13 and Over)

HPHPA is a clostridia metabolite and dysbiosis marker and stands for 3-(3-hydroxyphenyl)-3-hydroxypropionic acid.

Learn more

HPHPA (Males Under Age 13)

HPHPA is a clostridia metabolite and dysbiosis marker and stands for 3-(3-hydroxyphenyl)-3-hydroxypropionic acid.

Learn more

HVA / VMA Ratio

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

Learn more

HVA / VMA Ratio (Males Age 13 and Over)

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

Learn more

HVA / VMA Ratio (Males Under Age 13)

The Organic Acids Test measures levels of HVA (homovanillic acid) and VMA (vanillylmandelic acid), the metabolites of the neurotransmitters, dopamine and epinephrine/norepinephrine. It also measures the ratio of the two metabolites.

Learn more

HVA/ DOPAC Ratio

HVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.

Learn more

HVA/ DOPAC Ratio (Males Age 13 and Over)

HVA and DOPAC are the major metabolites of dopamine. HVA stands for Homovanillic acid and DOPAC stands for Dihydroxyphenylacetic.

Learn more

HVA/ DOPAC Ratio (Males Under Age 13)

Kynurenic

Kynurenic Acid is product of the metabolism of L-Tryptophan and appears in urine in Vitamin B6 deficiencies. Your body needs vitamin B6 (pyridoxine) to utilize amino acids derived from dietary protein.

Learn more

Kynurenic (Males Age 13 and Over)

Kynurenic Acid is product of the metabolism of L-Tryptophan and appears in urine in Vitamin B6 deficiencies. Your body needs vitamin B6 (pyridoxine) to utilize amino acids derived from dietary protein.

Learn more

Kynurenic (Males Under Age 13)

Lactic

Formed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.

Learn more

Lactic (Males Age 13 and Over)

Formed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.

Learn more

Lactic (Males Under Age 13)

Formed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.

Learn more

Malic

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

Learn more

Malic (Males Age 13 and Over)

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

Learn more

Malic (Males Under Age 13)

Malic Acid is involved in the citric acid cycle (aka. Krebs cycle). The citric acid cycle is a series of reactions that occur in the mitochondrion to generate chemical energy that fuels the metabolism.

Learn more

Malonic

Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competiti

Learn more

Malonic (Males Age 13 and Over)

Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism. The name “Malonic” originates from Latin malum, meaning apple. Malonic acid is the archetypal example of a competiti

Learn more

Malonic (Males Under Age 13)

Mandelic

Mandelic acid is the major metabolite of styrene. Styrene (vinylbenzene) is used as an intermediate in plastic synthesis. Values less than 5 mg/L are due to normal metabolism of phenylalanine or tyrosine.

Learn more

Mandelic (Males Age 13 and Over)

Mandelic acid is the major metabolite of styrene. Styrene (vinylbenzene) is used as an intermediate in plastic synthesis. Values less than 5 mg/L are due to normal metabolism of phenylalanine or tyrosine.

Learn more

Mandelic (Males Under Age 13)

Methylcitric

Methylcitric is an organic acids that reflects decreased activity of the biotin-dependent enzyme propionyl-CoA carboxylase.

Learn more

Methylcitric (Males Age 13 and Over)

Methylcitric is an organic acids that reflects decreased activity of the biotin-dependent enzyme propionyl-CoA carboxylase.

Learn more

Methylcitric (Males Under Age 13)

Methylmalonic

Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.

Learn more

Methylmalonic (Males Age 13 and Over)

Methylmalonic acid (MMA) is a substance produced in very small amounts and is necessary for human metabolism and energy production.

Learn more

Methylmalonic (Males Under Age 13)

Methylsuccinic

Methylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids.

Learn more

Methylsuccinic (Males Age 13 and Over)

Methylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids.

Learn more

Methylsuccinic (Males Under Age 13)

Methylsuccinic acid is a normal metabolite found in human fluids and is an intermediate metabolite in the breakdown of fatty acids.

Learn more

N-Acetylaspartic

Elevated N-acetylaspartic acid is due to the genetic disorder Carnavan’s disease, a potentially fatal disease causing spongy degeneration of the brain.  What is Carnavan’s disease? Canavan disease is a rare inherited disorder t

Learn more

N-Acetylaspartic (Males Age 13 and Over)

Elevated N-acetylaspartic acid is due to the genetic disorder Carnavan’s disease, a potentially fatal disease causing spongy degeneration of the brain.  What is Carnavan’s disease? Canavan disease is a rare inherited disorder t

Learn more

N-Acetylaspartic (Males Under Age 13)

N-Acetylcysteine (NAC)

N-Acetylcysteine (NAC) is a powerful antioxidant that increases the glutathione reserves in the body.  Together with glutathione, N-Acetylcysteine (NAC) directly binds to toxic metabolites. Although N-Acetylcysteine (NAC) may be benefici

Learn more

N-Acetylcysteine (NAC) (Males Age 13 and Over)

N-Acetylcysteine (NAC) is a powerful antioxidant that increases the glutathione reserves in the body.  Together with glutathione, N-Acetylcysteine (NAC) directly binds to toxic metabolites. Although N-Acetylcysteine (NAC) may be benefici

Learn more

N-Acetylcysteine (NAC) (Males Under Age 13)

Orotic

Orotic Acid is a sensitive marker of your liver’s capacity to convert toxic ammonia to non-toxic urea that you can excrete. That capacity can be increased by additional arginine. Ammonia toxicity can also be reduced by

Learn more

Orotic (Females Under Age 13)

Orotic Acid is a sensitive marker of your liver’s capacity to convert toxic ammonia to non-toxic urea that you can excrete. That capacity can be increased by additional arginine. Ammonia toxicity can also be reduced by

Learn more

Orotic (Males Age 13 and Over)

Orotic Acid is a sensitive marker of your liver’s capacity to convert toxic ammonia to non-toxic urea that you can excrete. That capacity can be increased by additional arginine. Ammonia toxicity can also be reduced by

Learn more

Orotic (Males Under Age 13)

Oxalic

Oxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin

Learn more

Oxalic (Females Under Age 13)

Oxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin

Learn more

Oxalic (Males Age 13 and Over)

Oxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin

Learn more

Oxalic (Males Under Age 13)

Oxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, Candida, or high dose vitamin C. If yeast or fungal markers are elevated, antifungal therapy may reduces oxalates. Also associated with anti-freeze (ethylene glycol) poisonin

Learn more

Pantothenic (B5)

Pantothenic acid is an essential B vitamin (=Vitamin B5) that is converted to coenzyme A (unrelated to vitamin A). Coenzyme A is needed for the synthesis of fatty acids, cholesterol, and acetyl choline and is also needed for the Krebs cycle and fatty

Learn more

Pantothenic (B5) (Males Age 13 and Over)

Pantothenic acid is an essential B vitamin (=Vitamin B5) that is converted to coenzyme A (unrelated to vitamin A). Coenzyme A is needed for the synthesis of fatty acids, cholesterol, and acetyl choline and is also needed for the Krebs cycle and fatty

Learn more

Pantothenic (B5) (Males Under Age 13)

Pantothenic acid is an essential B vitamin (=Vitamin B5) that is converted to coenzyme A (unrelated to vitamin A). Coenzyme A is needed for the synthesis of fatty acids, cholesterol, and acetyl choline and is also needed for the Krebs cycle and fatty

Learn more

Phenyllactic

Phenyllactic acid is a metabolite of phenylalanine.

Learn more

Phenyllactic (Males Age 13 and Over)

Phenyllactic acid is a metabolite of phenylalanine.

Learn more

Phenyllactic (Males Under Age 13)

Phenylpyruvic

Phenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. 

Learn more

Phenylpyruvic (Males Age 13 and Over)

Phenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. 

Learn more

Phenylpyruvic (Males Under Age 13)

Phosphoric

Phosphoric acid is a marker of vitamin D and calcium. This marker indicates whether vitamin D receptors are activated. If phosphoric acid is low, then the person is likely vitamin D and/or calcium deficient. Low levels can be due to low phosphat

Learn more

Phosphoric (Males Age 13 and Over)

Phosphoric acid is a marker of vitamin D and calcium. This marker indicates whether vitamin D receptors are activated. If phosphoric acid is low, then the person is likely vitamin D and/or calcium deficient. Low levels can be due to low phosphat

Learn more

Phosphoric (Males Under Age 13)

Pyridoxic (B6)

A major metabolite of vitamin B6. High pyridoxic acid indicates high recent intake of vitamin B6. Because some individuals may require very high doses of vitamin B6, high values do not necessarily indicate the need to reduce vitamin B6 intake. Low va

Learn more

Pyridoxic (B6) (Males Age 13 and Over)

The main urinary metabolite of pyridoxine (Vitamin B6) and is a measure of recent dietary intake. Low values of pyridoxic acid in the urine indicate low recent intake while high values indicate high recent dietary intake.

Learn more

Pyridoxic (B6) (Males Under Age 13)

Pyroglutamic

Pyroglutamate (or Pyroglutamic acid) is an intermediate in the glutathione metabolism and a marker of glutathione deficiency.

Learn more

Pyroglutamic (Males Age 13 and Over)

Pyroglutamate (or Pyroglutamic acid) is an intermediate in the glutathione metabolism and a marker of glutathione deficiency.

Learn more

Pyroglutamic (Males Under Age 13)

Pyruvic

Pyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids.

Learn more

Pyruvic (Females Under Age 13)

Pyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids.

Learn more

Pyruvic (Males Age 13 and Over)

Pyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids.

Learn more

Pyruvic (Males Under Age 13)

Quinolinic

Quinolinic acid is a neurotoxic substance produced by our own bodies and a metabolite of tryptophan.

Learn more

Quinolinic (Males Age 13 and Over)

Quinolinic acid is a neurotoxic substance produced by our own bodies and a metabolite of tryptophan.

Learn more

Quinolinic (Males Under Age 13)

Quinolinic / 5-HIAA Ratio

A high ratio of quinolinic acid to the tryptophan metabolite, 5-hydroxyindoleacetic acid, indicates excessive inflammation due to recurrent infections, excessive tryptophan intake, immune overstimulation, excessive adrenal production of cortisol, or

Learn more

Sebacic

Increased urinary products of the omega fatty acid metabolism pathway may be due to carnitine deficiency, fasting, or increased intake of triglycerides from coconut oil, or some infant formulas.

Learn more

Sebacic (Males Age 13 and Over)

Increased urinary products of the omega fatty acid metabolism pathway may be due to carnitine deficiency, fasting, or increased intake of triglycerides from coconut oil, or some infant formulas.

Learn more

Sebacic (Males Under Age 13)

Suberic

Suberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.

Learn more

Suberic (Males Age 13 and Over)

Suberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.

Learn more

Suberic (Males Under Age 13)

Suberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.

Learn more

Succinic

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Learn more

Succinic (Females Under Age 13)

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Learn more

Succinic (Males Age 13 and Over)

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Learn more

Succinic (Males Under Age 13)

Tartaric

Breakdown product of hyaluronic acid; also found in some foods.

Learn more

Tartaric (Males Age 13 and Over)

Breakdown product of hyaluronic acid; also found in some foods.

Learn more

Tartaric (Males Under Age 13)

Breakdown product of hyaluronic acid; also found in some foods.

Learn more

Thymine

A pyrimidine (DNA building block) that is elevated in the genetic disease dihydropyrimidine dehydrogenase deficiency. In this genetic disease, the pyrimidine uracil is also elevated. - Thymine is one of the five bases used to build nucleic acids.

Learn more

Thymine (Males Age 13 and Over)

A pyrimidine (DNA building block) that is elevated in the genetic disease dihydropyrimidine dehydrogenase deficiency. In this genetic disease, the pyrimidine uracil is also elevated. - Thymine is one of the five bases used to build nucleic acids.

Learn more

Thymine (Males Under Age 13)

Tricarballylic

A chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate

Learn more

Tricarballylic (Females Under Age 13)

A chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate

Learn more

Tricarballylic (Males Age 13 and Over)

A chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate

Learn more

Tricarballylic (Males Under Age 13)

A chemical byproduct released from fumonisins during passage through the gastrointestinal tract. Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused by the intake of corn or corn-based food contaminate

Learn more

Uracil

The pyrimidine metabolites are markers of folate metabolism. The two markers are uracil and thymine. Folate acts as a methyl donor in converting uracil to thymine. Elevated values of uracil suggest folic acid deficiency. Folate is needed to conver

Learn more

Uracil (Males Age 13 and Over)

The pyrimidine metabolites are markers of folate metabolism. The two markers are uracil and thymine. Folate acts as a methyl donor in converting uracil to thymine. Elevated values of uracil suggest folic acid deficiency. Folate is needed to conver

Learn more

Uracil (Males Under Age 13)

The pyrimidine metabolites are markers of folate metabolism. The two markers are uracil and thymine. Folate acts as a methyl donor in converting uracil to thymine. Elevated values of uracil suggest folic acid deficiency. Folate is needed to conver

Learn more

Vanillylmandelic (VMA)

Metabolite of epinephrine and norepinephrine. Often elevated due to stress induced catecholamine output or lead toxicity.

Learn more

Vanillylmandelic (VMA) (Males Age 13 and Over)

Metabolite of epinephrine and norepinephrine. Often elevated due to stress induced catecholamine output or lead toxicity.

Learn more

Vanillylmandelic (VMA) (Males Under Age 13)