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Optimal range: 40 - 80 %
Cerebrospinal fluid (CSF) is a clear liquid that cushions and surrounds the brain and spinal cord. It helps support the venous structures around the brain, and it’s important in brain homeostasis and metabolism. This fluid is continually replenished by the choroid plexus in the brain and absorbed into the bloodstream. The body completely replaces CSF every few hours.
The WBC count seen in normal adult CSF is comprised of approximately 70 percent lymphocytes and 30 percent monocytes. There are two forms of lymphocytes: B cells, which make antibodies, and T cells, which recognize and remove foreign substances.
Lymphocytes, when found in cerebrospinal fluid (CSF) as part of a Cell Count and Differential panel, provide critical insights into the immunological and pathological status of the central nervous system (CNS). The presence and concentration of lymphocytes in CSF are indicative of the immune response within the CNS and can be a marker for various conditions, including infections, autoimmune disorders, and malignancies.
Optimal range: 40 - 80 %
Lymphocytes (Lymphs) in cerebrospinal fluid (CSF) are an important marker often assessed during lab tests to evaluate the health of the central nervous system. Lymphocytes are a type of white blood cell that plays a critical role in the immune response. In the CSF, elevated levels of lymphs can indicate inflammation or infection, such as viral meningitis, autoimmune diseases, or certain cancers like lymphoma. Normal lymphocyte levels in the CSF typically suggest a healthy central nervous system. However, deviations from normal ranges may prompt further investigation to determine the underlying cause of the immune response within the brain and spinal cord.
Optimal range: 45 - 700 qmol/24 hours
LEARN MOREOptimal range: 139 - 437 umol/L
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
Optimal range: 4 - 69 mmol/mol creatinine
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.
Optimal range: 13.7 - 329.3 nmol/mg Creatinine
LEARN MOREOptimal range: 119 - 233 umol/L
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
Optimal range: 15.3 - 1020.6 umol/g Cr
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.
Optimal range: 13.7 - 34.7 qmol/dL
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
Optimal range: 32 - 300 qM/g creatinine
LEARN MOREOptimal range: 94 - 278 umol/L
Lysine is found in great quantities in muscle tissues, stimulates calcium absorption, carnitine synthesis, and growth and repair of muscle tissue.
Optimal range: 13.7 - 34.7 Units
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.
Optimal range: 15 - 231 micromol/g creatinine
Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.
Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.
Optimal range: 210.6 - 498.2 nmol/ML
Lysine catabolism leads to collagen and carnitine production.
- Higher plasma valine, lysine, and tyrosine were independently and positively associated with gestational diabetes mellitus and insulin activity.
- Increased urinary lysine was associated with a lower risk of chronic kidney disease (0.73 [0.50-0.90].
- Low lysine has been associated with increased anxiety in human and animal studies.
- Lysine and arginine supplementation were found to reduce anxiety and basal salivary cortisol levels in adults.
- Lower plasma lysine and glutamine levels, and higher glutamic acid, were significantly associated with ADHD.
Optimal range: 120 - 318 µmol/L , 12.00 - 31.80 µmol/dL
Lysine is found in great quantities in muscle tissues, stimulates calcium absorption, carnitine synthesis, and growth and repair of muscle tissue.
Optimal range: 11 - 175 micromol/g creatinine
Lysine is found in great quantities in muscle tissues, stimulates calcium absorption, carnitine synthesis, and growth and repair of muscle tissue.
Optimal range: 0 - 500 ng/mL
Lysozyme is an enzyme that catalyzes the hydrolysis of specific glycosidic bonds in mucopolysaccharides that constitute the cell wall of gram-positive bacteria. Lysozyme is an antibacterial defense present in the G.I. tract and is secreted by granulocytes, macrophages, Paneth cells, and Brunner's Glands as well as normal colonic crypt cells. The main source for fecal lysozyme is the intestinal granulocytes.
Optimal range: 0 - 575 ng/mL
Lysozyme is an enzyme that catalyzes the hydrolysis of specific glycosidic bonds in mucopolysaccharides that constitute the cell wall of gram-positive bacteria. Lysozyme is an antibacterial defense present in the G.I. tract and is secreted by granulocytes, macrophages, Paneth cells, and Brunner's Glands as well as normal colonic crypt cells. The main source for fecal lysozyme is the intestinal granulocytes.
Optimal range: 3 - 12.8 ug/ml
Serum lysozyme has emerged as a valuable biomarker for monitoring disease progression and regression, particularly in cases of confirmed sarcoidosis. According to revised FAB (French, American, British) criteria, serum or urine lysozyme levels that are three times the normal limit fulfill one of the key diagnostic criteria for distinguishing M4/M5 acute myeloid leukemia with monocytic differentiation from M2 acute myeloblastic leukemia with maturation.
Optimal range: 0 - 8.1 mmol/mol creatinine
m-Hydroxyphenylacetate (3-Hydroxyphenylacetic acid) and 4-hydroxyphenylacetic acid are produced by the bacterial fermentation of amino acids, much like Indoleacetic acid (IAA).