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Optimal range: 12 - 48 pg/mL
11-deoxycortisol is an adrenal hormone. It is the end product of 17-hydroxyprogesterone (17OHPg) through 21-hydroxylase synthesis and is the immediate precursor of cortisol.
Levels of these cortisol precursors and the enzymes that stimulate cortisol synthesis from them are typically increased when ACTH levels are increased, which can occur with Cushing syndrome, adrenal carcinoma, ACTH-producing tumors, or 11β-hydroxylase deficiency, a more rare form of CAH34 than seen with 21-hydroxylase deficiency, which constitutes > 95% of all CAH cases
Optimal range: 0.3 - 1.2 ng/mg Creat/Day
LEARN MOREOptimal range: 0.35 - 1.8 ng/mg Creat/Day
11-Deoxycortisol has very little glucocorticoid activity yet its role as an intermediate in cortisol creation may assist in understanding of impairment along this pathway. CYP21A (21-hydroxylase) is responsible for the conversion of 17-hydroxyprogesterone to 11-deoxycortisol.
Optimal range: 0.35 - 1.8 ng/mg Creat/Day
LEARN MOREOptimal range: 3.7 - 18.1 µmol/L
Eicosenoic acid has recently been reported as one of the five biomarkers for diagnosis of schizophrenia.
Optimal range: 1.3 - 4.1 micromol/24 hr
11-Hydroxy-androsterone is a that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 71 - 496 nmol/dL (SG)
11-Hydroxy-androsterone is a 5β-reduced compound that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 43 - 391 nmol/dL (SG)
11-Hydroxy-androsterone is a 5β-reduced compound that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 210 - 920 ng/mg Creat/Day
11-Hydroxy-Androsterone (OHAN) is a urinary metabolite of cortisol metabolism as well as 11-oxygenated androgens production from the adrenal glands. While research is limited in the significance of elevations of this metabolite, it may be associated with certain conditions like 21-hydroxylase deficiency and castration- resistant prostate cancer.
Optimal range: 180 - 800 ng/mg Creat/Day
OHAN is a urinary metabolite of cortisol metabolism as well as 11-oxygenated androgens production from the adrenal glands.
Optimal range: 250 - 1000 ng/mg Creat/Day
LEARN MOREOptimal range: 0.5 - 2.6 micromol/24 hr
11-Hydroxy-etiocholanolone is a compound that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 64 - 363 nmol/dL (SG)
11-Hydroxy-etiocholanolone is a compound that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 49 - 336 nmol/dL (SG)
11-Hydroxy-etiocholanolone is a compound that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 35 - 380 ng/mg Creat
LEARN MOREOptimal range: 40 - 470 ng/mg Creat/Day
OHET is the product of cortisol metabolism as well as 11-oxygenated androgens produced from the adrenal gland. Levels tend to reflect levels of etiocholanolone.
Optimal range: 20 - 710 ng/mg Creat/Day
LEARN MOREOptimal range: 0.3 - 1.9 micromol/24 hr
11-Keto-androsterone is a that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 37 - 236 nmol/dL (SG)
11-Keto-androsterone is a that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.
Optimal range: 46 - 258 nmol/dL (SG)
11-Keto-androsterone is a that is an end product of androgen catabolism.
In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group.
Androgens are important hormones in the health of both men and women. Testosterone and DHEA are metabolized into what is collectively known as the 17-ketosteroids (DHEA is formally included as a 17-ketosteroid). Together, these markers provide a comprehensive assessment of androgen sufficiency, as well as evaluating the need for, and monitoring of, androgen hormone therapy.