Complete Hormones (24hr)

Urine

Performed by: Genova Diagnostics

Biomarkers included in this panel:

11-Hydroxy-androsterone (24hr urine)

11-Hydroxy-androsterone is a that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health of both men

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11-Hydroxy-androsterone (FMV urine)

11-Hydroxy-androsterone is a 5β-reduced compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the

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11-Hydroxy-etiocholanolone (24hr urine)

11-Hydroxy-etiocholanolone is a compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health

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11-Hydroxy-etiocholanolone (FMV urine)

11-Hydroxy-etiocholanolone is a compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health

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11-Keto-androsterone (24hr urine)

11-Keto-androsterone is a that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health of both men and

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11-Keto-androsterone (FMV urine)

11-Keto-androsterone is a that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health of both men and

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11-Keto-etiocholanolone (24hr urine)

11-Keto-etiocholanolone is a compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the health of both

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11-Keto-etiocholanolone (FMV urine)

11-Keto-etiocholanolone is a 5β-reduced compound that is an end product of androgen catabolism. In the Genova complete hormone test this marker is part of the "Total 17-ketosteroids" group. Androgens are important hormones in the

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11b-HSD Index (FMV urine)

16a-Hydroxyestrone (16a-OH E1)

16α-Hydroxyestrone (16α-OH-E1), or hydroxyestrone, also known as estra-1,3,5(10)-trien-3,16α-diol-17-one, is an endogenous steroidal estrogen and a major metabolite of estrone, as well as an intermediate in the biosynthesis of estri

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16a-Hydroxyestrone (FMV urine)

17-Hydroxysteroids, Total

An elevated 17-hydroxysteroids total and/or cortisol total may be caused by stress, strenuous exercise, inflammation, hypoglycemia, insulin resistance, hypothyroidism, or licorice ingestion.

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17-Hydroxysteroids, Total (24hr urine)

An elevated 17-hydroxysteroids total and/or cortisol total may be caused by stress, strenuous exercise, inflammation, hypoglycemia, insulin resistance, hypothyroidism, or licorice ingestion.

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17-Ketosteroids Total (FMV urine)

ANDROGENS such as DHEA, testosterone, and androstenedione tend to be extensively metabolized into downstream androgen compounds. As a result, the levels of testosterone along with “Total 17-ketosteroids” (DHEA plus metabolites) should be

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17-Ketosteroids, Total (24hr urine)

2-Hydroxyestrone (FMV urine)

2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH(E1+E2)]

2-Hydroxyestrone/16a-Hydroxyestrone Ratio (FMV urine)

2-Methoxyestrone (FMV urine)

2-Methoxyestrone+2-Methoxyestradiol [2MeO(E1+E2)]

2-Methoxyestrone/2-Hydroxyestrone Ratio

2-OH(E1+E2) / 16a-OHE1

2-hydroxyestrone and 16-hydroxyestrone are Phase I metabolites of Estrone (E1). Their ratio is of clinical significance in pre and peri-menopausal women. In post-menopausal women it does not have the same clinical significance. It is, however, hypoth

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2-OH(E1+E2) / 2-MeO(E1+E2)

There is evidence that methoxylated estrogens, especially the 2-pathway methoxylated estrogens (E1 and E2), are associated with decreased breast cancer risk; 2-MeOE2, produced from 2-OHE2, has been described to have anti-proliferative, antingiogenic,

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4-Hydroxyestrone (FMV urine)

4-Hydroxyestrone+4-Hydroxyestradiol [4-OH(E1+E2)]

Research focus is shifting toward 4-hydroxyesterone which is thought to have greater estrogenic and genotoxic potential than either 2-hydroxyestrone or 16a-hydroxyestrone.

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4-Methoxyestrone (FMV urine)

4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)]

Most recent studies find an increased breast cancer risk associated with the ratio of 4-pathway cetechols to 4-pathway methylated catechols.

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5a-Reductase Activity (Etiocholanolone/Androsterone Ratio)

The Etiocholanolone/Androsterone (E/A) Ratio assesses androgen metabolism by comparing the enzymatic activity of 5β-reductase/5α-reductase.

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allo-Tetrahydrocortisol, a-THF (24hr urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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allo-Tetrahydrocortisol, a-THF (FMV urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Anabolic/Catabolic Balance (24hr urine)

This anabolic/catabolic balance – or the balance of ‘growth and healing’ versus ‘wear and tear’ in the body – can be assessed by comparing total 17-hydroxycorticosteroids with total 17-ketosteroids in the urine.

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Anabolic/Catabolic Balance (FMV)

The Anabolic/Catabolic Balance refers to the balance between "growth and healing" (anabolic) and "wear and tear" (catabolic) activity in the body. Both anabolic and catabolic metabolism are essential to health.

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Androstanediol (24hr urine)

The measurement of androstanediol, in addition to testosterone, is of interest for the evaluation of androgenic activity.

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Androstanediol (FMV urine)

The measurement of androstanediol, in addition to testosterone, is of interest for the evaluation of androgenic activity.

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Androsterone (24hr urine)

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways.

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Androsterone (FMV urine)

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways.

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Cortisol, Free (FMV urine)

DHEA (24hr urine)

DHEA is a hormone produced by both the adrenal gland and the brain. DHEA leads to the production of androgens and estrogens. DHEA levels in the body begin to decrease after age 30. Levels decrease more quickly in women.

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DHEA (FMV urine)

DHEA is a hormone produced by both the adrenal gland and the brain. DHEA leads to the production of androgens and estrogens. DHEA levels in the body begin to decrease after age 30. Levels decrease more quickly in women.

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E/A: 5b/5a Ratio (24hr urine)

The Etiocholanolone/Androsterone (E/A) Ratio assesses androgen metabolism by comparing the enzymatic activity of 5b-reductase/5a-reductase. Etiocholanolone is produced via the 5b-reductase pathway and androsterone is produced via the 5a-reductase pat

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E/A: 5b/5a Ratio (FMV urine)

The Etiocholanolone/Androsterone (E/A) Ratio assesses androgen metabolism by comparing the enzymatic activity of 5β-reductase/5α-reductase.

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Estradiol (E2) (24hr)

The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving abs

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Estradiol (E2) - Premenopause (luteal)

The most physiologically active estrogen. Binds to both to ER and Estrogen Receptor Beta (ERβ). Estradiol, made in the ovary, rapidly converts to estrone. Poor symptom control with estrogen replacement may suggest the need for improving abs

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Estriol (E3) (24hr)

Estriol (E3) is considered to be the mildest and briefest-acting of the three estrogens. Estrogens play a critical role in female sexual development, menstrual function, protein synthesis, cardiovascular function, bone formation and remodeling, co

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Estriol (E3) - Premenopause (luteal)

Estrone (E1) (24hr)

Estrone is the predominant estrogen in post-menopausal women and inter-converts with estradiol. This conversion is dependant on the bidirectional activity of 17-beta-hydroxysteroid dehydrogenase, which also converts testosterone to androstenedione (a

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Estrone (E1) - Premenopause (luteal)

Estrone is the predominant estrogen in post-menopausal women and inter-converts with estradiol. This conversion is dependant on the bidirectional activity of 17-beta-hydroxysteroid dehydrogenase, which also converts testosterone to androstenedione (a

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Etiocholanolone (24hr urine)

Etiocholanolone is an androstenedione and testosterone metabolite that is excreted in the urine. It is produced from androstenedione and the 5-alpha and 5-beta-reductase metabolic pathways. It is helpful in evaluating adrenal and androgen function.

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Etiocholanolone (FMV urine)

Etiocholanolone is an androstenedione and testosterone metabolite that is excreted in the urine. It is produced from androstenedione and the 5-alpha and 5-beta-reductase metabolic pathways. It is helpful in evaluating adrenal and androgen function.

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Pregnanediol (24hr urine)

Progesterone rapidly metabolizes by the time it reaches the urine, and its direct metabolite, pregnanediol, is a reflection of circulating progesterone concentrations.

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Pregnanediol (FMV urine)

Progesterone rapidly metabolizes by the time it reaches the urine, and its direct metabolite, pregnanediol, is a reflection of circulating progesterone concentrations.

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Pregnanetriol (24hr urine)

Progesterone is metabolized into numerous downstream compounds, but most immediately into pregnanediol and pregnanetriol. Urine levels of these metabolites tend to correlate with levels of serum progesterone, thus may be used to assess status of the

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Pregnanetriol (FMV urine)

Progesterone is metabolized into numerous downstream compounds, but most immediately into pregnanediol and pregnanetriol. Urine levels of these metabolites tend to correlate with levels of serum progesterone, thus may be used to assess status of the

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Testosterone (24hr urine)

Testosterone (FMV urine)

Testosterone is the major androgen in the body. It is converted to dihydrotestosterone by 5-alphareductase, and to estradiol by aromatase.

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Tetrahydrocortisol, THF (24hr urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrocortisol, THF (FMV urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrocortisone, THE (24hr urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrocortisone, THE (FMV urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrodeoxycortisol (FMV urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Tetrahydrodeoxycortisol, THS (24hr urine)

This marker is part of the "17-Hydroxysteroids" group. Please refer to the "17-Hydroxysteroids, Total" marker.

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Triiodothyronine, T3 (FMV urine)