The DPPX antibody test checks for autoantibodies against DPPX (DPP6), a neuronal cell-surface protein that helps regulate brain and nerve excitability. When present, these antibodies are linked to autoimmune DPPX encephalitis, a potentially treatable cause of symptoms like memory/behavior changes, agitation, tremor/myoclonus, sleep disturbance, seizures, and often prominent gastrointestinal symptoms (weight loss, diarrhea).
Genetic celiac disease marker
Genetic celiac disease marker
Fahrenheit
measures the presence of lupus anticoagulants
Detection of lupus anticoagulant
The dRVVT Screen Ratio is a key component of lupus anticoagulant (LA) testing. It is calculated from the dilute Russell's viper venom time (dRVVT) screen test, which uses a low-phospholipid reagent to increase sensitivity to lupus anticoagulant. A normal dRVVT screen ratio is typically less than 1.20, while an elevated ratio (≥1.20) may suggest the presence of LA. However, elevated results can also arise from coagulation factor deficiencies, anticoagulant medications, or other inhibitors. The screen ratio is determined by dividing the patient’s plasma clotting time by the clotting time of normal pooled plasma. When the ratio is elevated, additional tests, such as mixing studies and confirmatory assays, are often performed to distinguish lupus anticoagulant from other causes of prolonged clotting times. The dRVVT screen ratio is frequently used in combination with other tests, such as aPTT, as part of a comprehensive lupus anticoagulant panel. When incorporated into a reflexive testing algorithm, it has a sensitivity of approximately 65-70% for diagnosing lupus anticoagulant. This multi-step approach enhances diagnostic accuracy, particularly when interpreting complex coagulation abnormalities.
Evaluating patients with signs and symptoms consistent with systemic lupus erythematosus (SLE).
double stranded DNA
Dust Mite (Dermatophagoides pteronyssinus) IgE: What You Need to Know The "Dust Mite (Dermatophagoides pteronyssinus) IgE" test measures your body's immune response to a common allergen found in household dust mites. Dust mites, tiny creatures invisible to the naked eye, thrive in warm, humid environments like bedding, carpets, and furniture. When you inhale or come into contact with dust containing these mites, your immune system may react by producing specific antibodies called IgE (Immunoglobulin E) if you’re sensitive to them. High levels of Dermatophagoides pteronyssinus IgE indicate that your immune system recognizes dust mite proteins as a threat, which can trigger allergic reactions. Symptoms include sneezing, itching, nasal congestion, watery eyes, or even asthma symptoms in some cases. This test is helpful for diagnosing dust mite allergies, guiding treatment plans, and minimizing exposure to allergens. Why This Test is Important for Allergy Management If you've been struggling with respiratory symptoms at home or in environments where dust accumulates, this test can help pinpoint dust mites as a possible cause. Knowing your IgE level specific to Dermatophagoides pteronyssinus can help you work with your doctor to create an effective allergy management plan, which may include allergen-proofing your home, using air purifiers, and, if necessary, exploring allergy medications or immunotherapy. This test is especially valuable for individuals prone to allergies or asthma, as managing dust mite exposure can significantly improve quality of life and reduce the frequency and severity of allergic reactions.
Need for Microbiome Support
Genova’s data analysis has led to the development of unique dysbiosis patterns, related to key physiologic disruptions, such as immunosuppression and inflammation. These patterns may represent dysbiotic changes that could pose clinical significance.
to detect previous or ongoing infections with Ehrlichia chaffeensis
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10,000+ biomarkers explained · trends over time
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