Explore 10,000+ laboratory markers, in plain English.

Metabolite of the omega fatty acid pathway.

Metabolite of the omega fatty acid pathway.

Ethylmalonic acid is a significant marker often evaluated in clinical settings to provide insights into metabolic processes within the body. Elevated levels of this compound can indicate a variety of metabolic disturbances, particularly those involving fatty acid oxidation and mitochondrial function. Ethylmalonic acid is produced during the breakdown of certain fatty acids and is typically excreted in the urine. When its levels are higher than normal, it may suggest an underlying metabolic disorder, such as a deficiency in certain enzymes that are crucial for breaking down fatty acids properly. This can be seen in conditions like short-chain acyl-CoA dehydrogenase deficiency (SCADD), which is a rare inherited disorder. In addition, high ethylmalonic acid levels can also be associated with other factors such as dietary imbalances, especially excessive intake of certain fatty acids, or exposure to environmental toxins that affect mitochondrial function. By monitoring ethylmalonic acid levels, healthcare providers can better understand a patient's metabolic health and make more informed decisions regarding diagnosis, treatment, and dietary recommendations. This marker is particularly useful in identifying issues related to energy production and overall mitochondrial health, which are critical for maintaining optimal physiological function.

often used in a variety of cosmetics and personal-care products

DHEA metabolite with 5-beta preference

DHEA metabolite with 5-beta preference

DHEA metabolite with 5-beta preference

Hormone test

androstenedione and testosterone metabolite

androstenedione and testosterone metabolite

Hormone test

Etiocholanolone is a 5-beta reduced isomer of androsterone, and a major metabolite of testosterone and androstenedione, however it is not active as an androgen.

of only minor clinical importance

part of the Lachnospiraceae family

part of the Lachnospiraceae family that is in the Firmicutes phylum

accounts for up to 13% of the gut microbiota

part of the Lachnospiraceae family and produces butyrate