Suberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.

- Suberic acid is present in the urine of people with fatty acid oxidation disorders.

- A metabolic breakdown product derived from oleic acid.

- Elevated levels of this unsaturated dicarboxylic acid are found in individuals with medium-chain acyl-CoA dehydrogenase deficiency (MCAD).

- Elevated in Schizophrenics

- People with metabolic syndrome or diabetes had significantly elevated adipic acid, suberic acid, lactic acid, and fumaric acid.

- Ketosis is sometimes accompanied by excessive excretion of adipic and suberic acid.

- Suberic acid is present in the urine of people with fatty acid oxidation disorders.

- A metabolic breakdown product derived from oleic acid.

- Elevated levels of this unsaturated dicarboxylic acid are found in individuals with medium-chain acyl-CoA dehydrogenase deficiency (MCAD).

- Elevated in Schizophrenics

- People with metabolic syndrome or diabetes had significantly elevated adipic acid, suberic acid, lactic acid, and fumaric acid.

- Ketosis is sometimes accompanied by excessive excretion of adipic and suberic acid.

Dietary fatty acids are metabolized into fuel sources using beta-oxidation. Fatty acid conversion into Acetyl-CoA requires transport across the mitochondrial membrane via the carnitine shuttle. When beta-oxidation is impaired, fats are metabolized using an alternate pathway called omega-oxidation. Omega-oxidation results in elevated levels of dicarboxylic acids such as adipic acid and suberic acid. Impaired beta-oxidation occurs in carnitine deficiency or enzymatic dysfunction due to lack of nutrient cofactors. Vitamin B2 and magnesium play a role in optimizing beta-oxidation.

Dietary fatty acids are metabolized into fuel sources using beta-oxidation. Fatty acid conversion into Acetyl-CoA requires transport across the mitochondrial membrane via the carnitine shuttle. When beta-oxidation is impaired, fats are metabolized using an alternate pathway called omega-oxidation. Omega-oxidation results in elevated levels of dicarboxylic acids such as adipic acid and suberic acid. Impaired beta-oxidation occurs in carnitine deficiency or enzymatic dysfunction due to lack of nutrient cofactors. Vitamin B2 and magnesium play a role in optimizing beta-oxidation.

Suberic acid is an important organic compound that can be measured to gain insights into metabolic processes within the body. It is a dicarboxylic acid, meaning it has two carboxyl groups (-COOH) at each end of its molecular structure. This compound is naturally produced during the breakdown of fatty acids, specifically through a process called beta-oxidation. Elevated levels of suberic acid in the body can indicate issues with fatty acid metabolism, which may be due to a deficiency in specific nutrients like carnitine, necessary for transporting fatty acids into the mitochondria where they are broken down for energy. Additionally, high suberic acid levels might suggest mitochondrial dysfunction, where the energy-producing organelles in cells are not working efficiently. This can result from various factors, including genetic conditions, nutrient deficiencies, or environmental toxins. Monitoring suberic acid levels can thus be a valuable tool for identifying metabolic imbalances and guiding nutritional and therapeutic interventions to restore optimal metabolic function.

Suberic Acid, Adipate, and Ethylmalonate elevations can indicate that you may need additional carnitine and/or vitamin B2 to assist your cells in converting fats into energy efficiently.

Suberylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body. Succinic acid is a key intermediate of both the Kreb’s cycle and the electron transport chain that generates adenosine triphosphate (ATP), the currency for most of the body’s energy transactions.

Succinate is produced from bacterial degradation of unabsorbed glutamine and is a metabolite of alpha-ketogluturate, as well as methionine, valine & leucine; precursor of fumaric acid; also formed from bacterial action on glutamine.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.