The measurement of androstanediol, in addition to testosterone, is of interest for the evaluation of androgenic activity.

DHEA and androstenedione are made almost exclusively by the adrenal gland (although a smaller amount is made in the ovaries). These hormones appear in urine as DHEA-S (DHEA-Sulfate), androsterone and etiocholanolone.

Androstenedione is secreted predominantly by the adrenal gland and production is controlled, in part, by adrenocorticotropic hormone (ACTH). It is also produced in the testes and ovaries from DHEA-S. It is a weak androgen and an intermediate in the biosynthesis of testosterone and estrone from DHEA. It has been found to have some estrogenic activity.

Androstenedione is converted to estrone by the action of aromatase in fat tissue.

Androstenedione, a crucial androgenic steroid, is a notable marker in the ZRT Laboratory Urinary Neurotransmitters panel, reflecting its significant role in male health and endocrinology. In men, androstenedione serves as a vital precursor in the biosynthesis of testosterone and estrogen, hormones pivotal for maintaining various physiological functions. Produced primarily in the adrenal glands and testes, optimal levels of androstenedione are essential for supporting male sexual development, muscle mass, bone density, and overall energy levels.

Androstenedione is a weak androgen secreted by adrenal glands, testes, and ovaries that is converted to testosterone or estrone in the periphery.

DHEA and androstenedione are made almost exclusively by the adrenal gland (although a smaller amount is made in the ovaries). These hormones appear in urine as DHEA-S (DHEA-Sulfate), androsterone and etiocholanolone.

Androstenetriol (5-AT), a metabolite of the hormone dehydroepiandrosterone (DHEA), is a noteworthy marker in the Comprehensive 24-Hour Urine Steroid Hormone Profile Test, emphasizing its relevance in evaluating adrenal function and overall health status in men. As an indicator of adrenal gland activity, 5-AT plays a significant role in the body's response to stress and immune system regulation. The measurement of 5-AT levels in a 24-hour urine sample offers a comprehensive overview of adrenal function over an extended period, providing deeper insights than single-point blood tests. This marker is particularly valuable in assessing conditions such as adrenal fatigue or insufficiency, where 5-AT levels may be diminished.

Androsterone is a metabolite of androgens, crucial for evaluating hormonal balance in women. Chemically classified as a 17-ketosteroid, androsterone is primarily a breakdown product of testosterone, but it can also be derived from other androgens. In women, the measurement of androsterone in a morning void urine sample offers valuable insights into androgenic activity, which plays a vital role in various physiological processes, including libido, energy levels, and overall well-being.

Androsterone is a DHEA metabolite via the 5-alpha-reductase pathway. The 5-alpha pathway is more androgenic. 

Androsterone is a DHEA metabolite via the 5-alpha-reductase pathway. The 5-alpha pathway is more androgenic. 

Androsterone is a DHEA metabolite via the 5-alpha-reductase pathway. The 5-alpha pathway is more androgenic. 

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways.

The ratio of Androsterone (5a) to Etiocholanolone (5b) in a Human Urinary Metabolic Profile (HUMAP) panel is a critical marker for assessing the balance of androgen metabolism in the body. Androsterone and Etiocholanolone are both metabolites of testosterone and other androgens, but they differ in their origins and physiological impacts. Androsterone, derived predominantly from the metabolism of testosterone, is associated with androgenic properties, playing a role in male characteristics and anabolic functions. In contrast, Etiocholanolone, though also a testosterone metabolite, does not possess androgenic activity and is a product of the 5β-reductase pathway.

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways.

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways.