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Lymphocyte Subset Panel 2

Optimal range:   50 - 375 #/cumm

CD1656 are an important NK (Natural killer) cell subset.

- NK cells are best known for killing virally infected cells, and detecting and controlling early signs of cancer. As well as protecting against disease, specialized NK cells are also found in the placenta and may play an important role in pregnancy.

- Natural killer T (NKT) cells represent a specialized T-cell population that is distinct from conventional T cells. They express an invariant T-cell receptor (TCR) that recognizes self and bacterial glycosphingolipid antigens presented by the MHC class I-like molecule, CD1d.

- Human natural killer (NK) cells can be subdivided in several subpopulations on the basis of the relative expression of the adhesion molecule CD56 and the activating receptor CD16. 

- NK cells serve an important role in host defense against viral infections, as well as tumor surveillance. They are also a component of the adaptive immune response through cytokine production.

- NK cell functions are governed by a balance between activating receptors and inhibitory receptors.

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Micronutrient (Vibrant America), Vibrant America

Optimal range:   1.18 - 3.74 x10E3/uL

The "Lymphocyte Count" is an important marker on the Micronutrient panel from VibrantAmerica. Lymphocytes are a type of white blood cell crucial for the body's immune system. They play a significant role in defending the body against infections, viruses, and other harmful invaders. The lymphocyte count measures the number of lymphocytes present in your blood. A healthy lymphocyte count indicates a well-functioning immune system, capable of effectively fighting off infections and diseases. Conversely, an abnormal lymphocyte count, whether too high or too low, can signal underlying health issues. For example, a low lymphocyte count might indicate a compromised immune system, making the body more susceptible to infections and illnesses, while a high count could suggest the presence of an ongoing infection or an autoimmune disorder where the body mistakenly attacks its own tissues. Regular monitoring of your lymphocyte count through panels like the Micronutrient panel from VibrantAmerica helps in early detection and management of potential health problems, ensuring that your immune system remains robust and effective in protecting your overall health.

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White Blood Cell Differential Test

Optimal range:   0.7 - 3.1 x10E3/uL , 700 - 3100 cells/uL

Lymphocytes are a type of white blood cell that plays a key role in the immune system. They help the body detect and fight infections caused by viruses, bacteria, and other harmful invaders. Lymphocytes are produced in the bone marrow and circulate through the blood and lymphatic system to monitor the body for potential threats.

There are three main types of lymphocytes: T cells, which regulate immune responses and destroy infected cells; B cells, which produce antibodies that target pathogens; and natural killer (NK) cells, which rapidly eliminate virus-infected or abnormal cells. Together, these cells help protect the body and create immune memory after infections or vaccinations.

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White Blood Cell Differential Test

Optimal range:   20 - 40 %

What Are Lymphocytes and What Do They Do?

Lymphocytes are a type of white blood cell that plays a vital role in your immune system. They help your body fight off diseases and infections by identifying and targeting harmful invaders like bacteria, viruses, and toxins. As part of a complex network of immune cells, lymph nodes, lymphatic tissues, and organs, lymphocytes are essential for maintaining your body’s defense system.

Types of Lymphocytes

  1. T Lymphocytes (T Cells):

    • T cells regulate the immune system’s response and directly attack infected or cancerous cells.
  2. B Lymphocytes (B Cells):

    • B cells produce antibodies—proteins that specifically target viruses, bacteria, and other foreign substances.
  3. Natural Killer (NK) Cells:

    • Unlike T cells, NK cells can destroy tumor cells and infected cells without needing prior activation, providing a rapid immune response.

How Lymphocytes Work

Lymphocytes have the unique ability to remember antigens, which are foreign substances that trigger an immune reaction. After encountering an antigen, some lymphocytes become memory cells. These memory cells enable the immune system to respond faster and more effectively when exposed to the same antigen again. This mechanism is the foundation of how vaccines protect against certain diseases.

Lymphocytes are constantly surveying the body, searching for antigens—from the common cold to cancerous cells. They interact with other immune cells, such as phagocytes (e.g., monocytes and macrophages) and specialized cells like dendritic cells, to coordinate a targeted immune response.

In summary, lymphocytes are key players in your immune system, working to detect, respond to, and remember harmful invaders, ensuring long-term protection and immunity.

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Lymphocytes, %

Synovial fluid

Cell Count and Differential, Synovial Fluid, Quest Diagnostics

Optimal range:   0 - 74 %

Lymphocytes are a type of white blood cell that plays a key role in the immune system. They are responsible for recognizing and combating infections, including viral and autoimmune diseases.

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Cell Count and Differential, Synovial Fluid, Quest Diagnostics

Optimal range:   40 - 80 %

Cerebrospinal fluid (CSF) is a clear liquid that cushions and surrounds the brain and spinal cord. It helps support the venous structures around the brain, and it’s important in brain homeostasis and metabolism. This fluid is continually replenished by the choroid plexus in the brain and absorbed into the bloodstream. The body completely replaces CSF every few hours.

The WBC count seen in normal adult CSF is comprised of approximately 70 percent lymphocytes and 30 percent monocytes. There are two forms of lymphocytes: B cells, which make antibodies, and T cells, which recognize and remove foreign substances.

Lymphocytes, when found in cerebrospinal fluid (CSF) as part of a Cell Count and Differential panel, provide critical insights into the immunological and pathological status of the central nervous system (CNS). The presence and concentration of lymphocytes in CSF are indicative of the immune response within the CNS and can be a marker for various conditions, including infections, autoimmune disorders, and malignancies.

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Lymphs, CSF

Spinal fluid

Cerebrospinal Fluid (CSF) Analysis

Optimal range:   40 - 80 %

Lymphocytes (Lymphs) in cerebrospinal fluid (CSF) are an important marker often assessed during lab tests to evaluate the health of the central nervous system. Lymphocytes are a type of white blood cell that plays a critical role in the immune response. In the CSF, elevated levels of lymphs can indicate inflammation or infection, such as viral meningitis, autoimmune diseases, or certain cancers like lymphoma. Normal lymphocyte levels in the CSF typically suggest a healthy central nervous system. However, deviations from normal ranges may prompt further investigation to determine the underlying cause of the immune response within the brain and spinal cord.

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Lysine

Blood

NutriStat Basic Profile, US BioTek

Optimal range:   139 - 437 umol/L

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

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LYSINE

Urine

Amino Acid Analysis, LC/MS, Quest Diagnostics

Optimal range:   4 - 69 mmol/mol creatinine

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.

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Amino Acid Profile, Qn (Plasma), Labcorp: What It Is, What It Tests, and How to Get Your Lab Results

Optimal range:   94 - 278 umol/L

Lysine is found in great quantities in muscle tissues, stimulates calcium absorption, carnitine synthesis, and growth and repair of muscle tissue.

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Amino Acid Profile, Qn (Urine), Labcorp: What It Is, What It Tests, and How to Get Your Lab Results

Optimal range:   15.3 - 1020.6 umol/g Cr

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.

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3102 ION (Blood/Urine) Amino Acids 40, Genova Diagnostics

Optimal range:   13.7 - 34.7 qmol/dL

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

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3000 NutrEval FMV - Urine and Blood, Genova Diagnostics

Optimal range:   13.7 - 34.7 Units

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

L-lysine supplementation has also been studied for herpes simplex treatment and prophylaxis and may be beneficial.

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3200 Metabolomix+ - FMV Urine, Genova Diagnostics

Optimal range:   15 - 231 micromol/g creatinine

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

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Amino Acid Analysis, Quest Diagnostics

Optimal range:   119 - 233 umol/L

Lysine is a nutritionally essential amino acid abundant in meat, fish, fowl, and legumes and is needed for formation of body proteins and enzymes.

Lysine can be methylated using S-adenosylmethionine (SAM) to synthesize carnitine, which is needed for fatty acid oxidation. Lysine also generates Acetyl CoA for use in the citric acid cycle. Lysine, proline, hydroxyproline, and vitamin C are important in the synthesis of collagen for skin, bones, tendons and cartilage.

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OMX Organic Metabolomics / Diagnostic Solutions, Diagnostic Solutions Laboratory | GI-MAP & Food Sensitivity Tests

Optimal range:   210.6 - 498.2 nmol/ML

Lysine catabolism leads to collagen and carnitine production.

- Higher plasma valine, lysine, and tyrosine were independently and positively associated with gestational diabetes mellitus and insulin activity.

- Increased urinary lysine was associated with a lower risk of chronic kidney disease (0.73 [0.50-0.90].

- Low lysine has been associated with increased anxiety in human and animal studies.

- Lysine and arginine supplementation were found to reduce anxiety and basal salivary cortisol levels in adults.

- Lower plasma lysine and glutamine levels, and higher glutamic acid, were significantly associated with ADHD.

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