Organic Acids, Plasma
Organic Acids, Urine assay, is the preferred test when screening for inherited disorders of metabolism. This plasma test is not as sensitive and will only detect the organic acids listed.
2-Ketoisocaproic AcidOptimal range: 20 - 75 umol/L
2-Ketoisocaproic Acid is a B-Complex Vitamin Marker (Leucine catabolism).
2-Ketoisocaproic Acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.LEARN MORE
2-Ketoisovaleric AcidOptimal range: 3 - 20 umol/L
AKA: alpha-Ketoisovaleric acid
Alpha-Ketoisovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids.LEARN MORE
Citric AcidOptimal range: 0 - 100 umol/L
Citric acid, cis-aconitic acid, and isocitric acid are the first three metabolites in the Krebs Citric Acid energy production cycle, which operates in the mitochondria of your cells.LEARN MORE
Lactic AcidOptimal range: 600 - 2600 umol/L
Formed from pyruvate in anaerobic or oxygen-starved (hypoxic) conditions to allow for ongoing production of ATP.LEARN MORE
Pyruvic AcidOptimal range: 20 - 140 umol/L
Pyruvic Acid feeds into the citric acid cycle & converts into acetyl CoA. Pyruvate is formed from carbohydrate via glucose or glycogen & secondarily from fats (glycerol) & glycogenic amino acids. Pyruvic acid is also formed from lactic acid with O2 and zinc.LEARN MORE